Requirement of Hos2 histone deacetylase for gene activity in yeast

Science

Volumn 298, Issue 5597, 2002, Pages 1412-1414

  Wang, Amy ^a   Kurdistani, Siavash K ^a   Grunstein, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; GENES;

GENE ACTIVATION;

YEAST;

HISTONE DEACETYLASE; HISTONE H3; HISTONE H4; HOS2 HISTONE DEACETYLASE; LYSINE; PROTEIN DERIVATIVE; PROTEIN SET3; UNCLASSIFIED DRUG;

GENE; YEAST;

ARTICLE; DEACETYLATION; GENE ACTIVATION; GENE ACTIVITY; GENE DELETION; GENETIC TRANSCRIPTION; GENOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE;

ACETYLATION; AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; CHROMATIN; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; HISTONE DEACETYLASES; MULTIGENE FAMILY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRECIPITIN TESTS; REPRESSOR PROTEINS; RNA, FUNGAL; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIRTUINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFORMATION, GENETIC;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037111879     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1077790     Document Type: Article

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22. We thank M. Longtine for his gift of plasmid pFA6a-13Myc-His3MX6. We are grateful to the members of M.G.'s laboratory, especially L. Milne, for their critical comments and discussion throughout this work. S.K.K. is a Howard Hughes Medical Institute Physician Postdoctoral Fellow. Supported by Public Health Service grant GM23674 of the NIH to M.G.