Internal dynamics and ionization states of the macrophage migration inhibitory factor: Comparison between wild-type and mutant forms

Biopolymers

Volumn 65, Issue 4, 2002, Pages 313-323

  Soares, T A ^a   Lins, R D ^a   Straatsma, T P ^b   Briggs, J M ^c  

^a ETH ZURICH   (Switzerland)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^c University of Houston   (United States)

Author keywords

Catalytic mechanism; Molecular dynamics; Poisson Boltzmann electrostatics

Indexed keywords

CATALYST ACTIVITY; ENZYMES; MOLECULAR DYNAMICS; RIGIDITY;

PROTONATION;

BIOPOLYMERS;

AMINE; GLYCINE; MACROPHAGE MIGRATION INHIBITION FACTOR; MUTANT PROTEIN; PROLINE; SOLVENT;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; COMPARATIVE STUDY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; HYDROPHOBICITY; IONIZATION; MOLECULAR DYNAMICS; NONHUMAN; PKA; PROTEIN STRUCTURE; PROTON TRANSPORT; SIMULATION; WILD TYPE;

BINDING SITES; HYDROGEN-ION CONCENTRATION; IONS; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; THERMODYNAMICS;

EID: 0037111511     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/bip.10252     Document Type: Article

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