High-performance liquid chromatographic assay for the determination of the novel C-Seco-taxane derivative (IDN 5390) in mouse plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 780, Issue 1, 2002, Pages 93-98

  Zaffaroni, M ^a   Frapolli, R ^a   Colombo, T ^a   Fruscio, R ^a   Bombardelli, E ^b   Morazzoni, P ^b   Riva, A ^b   D'Incalci, M ^a   Zucchetti, M ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b INDENA S P A   (Italy)

Author keywords

C Seco taxane derivatives; IDN 5390

Indexed keywords

BRIDGED COMPOUND; DRUG DERIVATIVE; IDN 5390; PACLITAXEL; TAXOID; 13 (N BUTYLOXYCARBONYL BETA ISOBUTYLISOSERINOYL) 10 DEHYDRO 10 DEACETYL C SECOBACCATIN; 9 METHYLETHER DERIVATIVE; ACETIC ACID; ACETONITRILE; ETHER DERIVATIVE; IDN 5517; TAXANE DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ANIMAL; ARTICLE; BLOOD; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; MOUSE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; ULTRAVIOLET SPECTROPHOTOMETRY; ANALYTIC METHOD; ANIMAL EXPERIMENT; CONTROLLED STUDY; DRUG BIOAVAILABILITY; ENZYME ASSAY; NONHUMAN; PLASMA; PRIORITY JOURNAL; SEPARATION TECHNIQUE; SOLID PHASE EXTRACTION; STANDARD;

ANIMALS; BRIDGED COMPOUNDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; MICE; PACLITAXEL; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET; TAXOIDS;

ACETIC ACID; ACETONITRILE; BIOASSAY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHARMACOKINETICS;

RETENTION TIMES;

BIOMEDICAL ENGINEERING;

EID: 0037111495     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-0232(02)00436-1     Document Type: Article

References (7)

1. Appendino G., Danieli B., Jakupovic J., Belloro E., Scambia G., Bombardelli E. Tetrahedron Lett. 38:1997;4273.
2. Distefano M., Scambia G., Ferlini C., Gallo D., De Vincenzo R., Filippini P., Riva A., Bombardelli E., Mancuso S. Anti-Cancer Drug Design. 13:1998;489.
3. Taraboletti G., Micheletti G., Rieppi M., Poli M., Turatto M., Rossi C., Borsotti P., Roccabianca P., Scanziani E., Nicoletti M.I., Bombardelli E., Morazzoni P., Riva A., Giavazzi R. Clin. Cancer Res. 8:2002;1182.
4. Supko J.G., Nair R.V., Seiden M.V., Lu H. J. Pharm. Biomed. Anal. 21:1999;1025.
5. Rouni M.R., Lotfolahi A., Stewart D.J., Molepo J.M., Shirazi F.H., Verginol J.C., Tomiak E., Delorme F., Vernillet L., Giguere M., Goel R. J. Pharm. Biomed. Anal. 17:1998;1243.
6. Sottani C., Minoia M.C., D'Incalci M., Paganin M., Zucchetti M. Rapid Commun. Mass Spectrom. 12:1998;251.
7. Sacchi-Landriani G., Guardabasso V., Rocchetti M. Comput. Programs Biomed. 16:1983;35.