The effect of pituitary adenylate cyclase activating polypeptide on cultured rat cardiocytes as a cardioprotective factor

Regulatory Peptides

Volumn 109, Issue 1-3, 2002, Pages 107-113

  Sano, Hirofumi ^a   Miyata, Atsuro ^a,b   Horio, Takeshi ^a   Nishikimi, Toshio ^a   Matsuo, Hisayuki ^a   Kangawa, Kenji ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Atrial natriuretic polypeptide; Cardiac myocyte; Cyclic AMP; Nonmyocyte

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CYCLIC AMP; DNA; ENDOTHELIN; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; MESSENGER RNA; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG EFFECT; HEART MUSCLE CELL; HEART PROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ATRIAL NATRIURETIC FACTOR; CARDIOTONIC AGENTS; CELLS, CULTURED; COLLAGEN; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; MYOCARDIUM; MYOCYTES, CARDIAC; NEUROPEPTIDES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; POLYMERASE CHAIN REACTION; RATS; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, TYPE I; RECEPTORS, PITUITARY HORMONE; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE, TYPE II; RNA, MESSENGER; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0037111294     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(02)00193-3     Document Type: Article

References (26)

1. Miyata A., Arimura A., Dahl R.R., Minamino N., Uehara A., Jiang L.et al. Isolation of a novel 38-residue hypothalamic polypeptide, which stimulates adenylate cyclase in pituitary cells. Biochem. Biophys. Res. Commun. 164:1989;567-574.
2. Miyata A., Jiang L., Dahl R.R., Kitada C., Kubo K., Fujino M.et al. Isolation of a neuropeptide corresponding to the N-terminal 27 residues of the pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38). Biochem. Biophys. Res. Commun. 170:1990;643-648.
3. Arimura A. Perspective on pituitary adenylate cyclase-activating polypeptide (PACAP) in the neuroendocrine, endocrine, and nervous systems. Jpn. J. Physiol. 48:1998;301-331.
4. Harmar A.J., Arimura A., Gozes I.et al. Nomenclature of receptors for vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP). Pharmacol. Rev. 50:1998;265-270.
5. Spengler D., Waeber C., Pantaloni C., Holsboer F., Bockaert J., Seeburg P.H.et al. Differential signal transduction by five splices variants of the PACAP receptor. Nature. 365:1993;170-175.
6. Vaudry D., Gonzalez B.J., Basille M., Yon L., Fournier A., Vaudry H. Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure and functions. Pharmacol. Rev. 52:2000;269-324.
7. Braas K.M., May V., Harakall S.A., Hardwick J.C., Parsons R.L. Pituitary adenylate cyclase-activating polypeptide expression and modulation of neuronal excitability in guinea pig cardiac ganglia. J. Neurosci. 18:1998;9766-9779.
8. Minkes R.K., McMahon T.J., Higuera T.R., Murphy W.A., Coy D.H., Kadowitz P.J. Analysis of systemic and pulmonary vascular responses to PACAP and VIP: role of adrenal catecholamines. Am. J. Physiol. 263:1992;H1659-H1669.
9. Sawangjaroen K., Dallemagen C.R., Cross R.B., Curlewis J.D. Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) on the cardiovascular system in sheep. Peptides. 13:1992;1029-1032.
10. Sawangjaroen K., Curlewis J.D. Effects of pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal polypeptide (VIP) on prolactin, luteinizing hormone and growth hormone secretion in the ewe. J. Neuroendocrinol. 6:1994;549-555.
11. Ross-Ascuitto N.T., Ascuitto R.J., Ramage D., Kydon D.W., Coy D.H., Kadowitz P.J. Pituitary adenylate cyclase-activating polypeptide: a neuropeptide with potent inotropic and coronary vasodilatory effects in neonatal pig hearts. Pediatr. Res. 34:1993;323-328.
12. Hirose M., Furukawa Y., Lakhe M., Chiba S. Regional differences in cardiac effects of pituitary adenylate cyclase-activating polypeptide-27 in the isolated dog heart. Eur. J. Pharmacol. 349:1998;269-276.
13. Suzuki N., Kasai K., Iino I., Takekoshi K., Oka M., Shimoda S.I. Anti-shock effect of pituitary adenylate cyclase-activating polypeptide (PACAP) on experimental endotoxin shock in dogs. Life Sci. 54:1994;389-394.
14. Runcie M.J., Ulman L.G., Potter E.K. Effects of pituitary adenylate cyclase-activating polypeptide on cardiovascular and respiratory responses in anaesthetized dogs. Regul. Pept. 60:1995;193-200.
15. Seebeck J., Schmidt W.E., Kilbinger H., Neumann J., Zimmermann N., Herzig S. PACAP induces bradycardia in guinea-pig heart by stimulation of atrial cholinergic neurons. Naunyn Schmiedeberg's Arch. Pharmacol. 354:1996;424-430.
16. Whalen E.J., Johnson A.K., Lewis S.J. Hemodynamic actions of systemically injected pituitary adenylate cyclase-activating polypeptide-27 in the rat. Eur. J. Pharmacol. 365:1999;205-221.
17. Bäsler I., Kuhn M., Müller W., Forssmann W.-G. Pituitary adenylate cyclase-activating polypeptide stimulates cardiodilatin/atrial natriuretic peptide (CDD/ANP)- (99-126) secretion from cultured neonatal rat myocardiocytes. Eur. J. Pharmacol. 291:1995;335-342.
18. Horio T., Nishikimi T., Yoshihara F., Matsuo H., Takishita S., Kangawa K. Effects of adrenomedullin on cultured rat cardiac myocytes and fibroblast. Eur. J. Pharmacol. 382:1999;1-9.
19. Nishikimi T., Horio T., Yoshihara F., Nagaya N., Matsuo H., Kangawa K. Effect of adrenomedullin on cAMP and cGMP levels in rat cardiac myocytes and nonmyocytes. Eur. J. Pharmacol. 353:1998;337-344.
20. Tamakawa H., Miyata A., Satoh K., Miyake Y., Matsuo H., Arimura A.et al. The augmentation of pituitary adenylate cyclase activating polypeptide (PACAP) in streptozotocin-induced diabetic rats. Peptides. 19:1998;1497-1502.
21. ATP current in rat atrial myocytes. Am. J. Physiol., Heart Circ. Physiol. 280:2001;H1058-H1065.
22. Miyata A., Satou K., Hino J., Tamakawa H., Matsuo H., Kangawa K. Rat aortic smooth muscle cells are bidirectionally regulated in a cell cycle-dependent manner via PACAP/VIP type 2 receptor. Ann. NY Acad. Sci. 865:1998;73-81.
23. Pfeffer J.M., Pfeffer M.A., Mirsky I., Braunwald E. Regression of left ventricular hypertrophy and prevention of left ventricular dysfunction by captopril in the spontaneously hypertensive rat. Proc. Natl. Acad. Sci. U. S. A. 79:1982;3310-3314.
24. Strand F.L. Neuropeptide: Regulators of Physiological Processes, a Bradford Book. 1999;MIT Press, Cambridge, MA.
25. Shields P.P., Glembotski C.C. Regulation of atrial natriuretic factor- (99-126) secretion from neonatal rat primary atrial cultures by activators of protein kinases A and C. J. Biol. Chem. 264:1989;9322-9328.
26. Weber K.T. Cardioreparation in hypertensive heart disease. Hypertension. 38:2001;588-591.