X-ray structure of a bifunctional protein kinase in complex with its protein substrate HPr

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 21, 2002, Pages 13437-13441

  Fieulaine, Sonia ^a   Morera, Solange ^a   Poncet, Sandrine ^b   Mijakovic, Ivan ^b   Galinier, Anne ^c   Janin, Joël ^a   Deutscher, Josef ^b   Nessler, Sylvie ^a  

^a LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

^b CEMAGREF   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; HISTIDINE PHOSPHOCARRIER PROTEIN; HISTIDINE PHOSPHOCARRIER PROTEIN KINASE; HISTIDINE PHOSPHOCARRIER PROTEIN PHOSPHORYLASE; PHOSPHATE; PHOSPHORYLASE; PROTEIN KINASE; PYROPHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL METABOLISM; CARBON UTILIZATION; CATALYSIS; CRYSTAL STRUCTURE; DEPHOSPHORYLATION; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; LACTOBACILLUS CASEI; PHOSPHATE TRANSPORT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; X RAY DIFFRACTION;

BACILLUS SUBTILIS; BACTERIAL PROTEINS; CALCIUM; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; LACTOBACILLUS CASEI; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); PHOSPHOENOLPYRUVATE SUGAR PHOSPHOTRANSFERASE SYSTEM; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); EUKARYOTA; LACTOBACILLUS; LACTOBACILLUS CASEI; POSIBACTERIA;

EID: 0037108941     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.192368699     Document Type: Article

References (35)

1. Hunter, T. (2000) Cell 100, 113-127.
2. Saier, M. H., Jr., Wu, L. F. & Reizer, J. (1990) Trends Biochem. Sci. 15, 391-395.
3. Stülke, J. & Hillen, W. (2000) Annu. Rev. Microbiol. 54, 849-880.
4. Deutscher, J., Galinier, A. & Martin-Verstraete, I. (2001) in Bacillus subtilis and Its Closest Relatives: From Genes to Cells, eds. Sonenschein, A. L., Hoch, J. A. & Losick, R. (Am. Soc. Microbiol., Washington, DC), pp. 129-150.
5. Miwa, Y., Nakata, A., Ogiwara, A., Yamamoto, M. & Fujita, Y. (2000) Nucleic Acids Res. 28, 1206-1210.
6. Moreno, M. S., Schneider, B. L., Maile, R. R., Weyler, W. & Saier, M. H. (2001) Mol. Microbiol. 39, 1366-1381.
7. Postma, P. W., Lengeler, J. W. & Jacobson, G. R. (1993) Microbiol. Rev. 57, 543-594.
8. Fujita, Y., Miwa, Y., Galinier, A. & Deutscher, J. (1995) Mol. Microbiol. 17, 953-960.
9. Galinier, A., Deutscher, J. & Martin-Verstraete, I. (1999) J. Mol. Biol. 286, 307-314.
10. Kravanja, M., Engelmann, R., Dossonnet, V., Blüggel, M., Meyer, H. E., Frank, R., Galinier, A., Deutscher, J., Schnell, N. & Hengstenberg, G. (1999) Mol. Microbiol. 31, 59-66.
11. Mijakovic, I., Poncet, S., Galinier, A., Fieulaine, S., Monedero, V., Janin, J., Nessler, S., Marquez, J. A., Scheffzek, K., Hengstenberg, W. & Deutscher, J. (2002) Proc. Natl. Acad. Sci. USA 99, 13442-13447.
12. Fieulaine, S., Morera, S., Poncet, S., Monedero, V., Gueguen-Chaignon, V., Galinier, A., Janin, J., Deutscher, J. & Nessler, S. (2001) EMBO J. 20, 3917-3927.
13. Matte, A., Goldie, H., Sweet, R. M. & Delbaere, L. T. (1996) J. Mol. Biol. 256, 126-143.
14. Galinier, A., Lavergne, J. P., Geourjon, C., Fieulaine, S., Nessler, S. & Jault, J. M. (2002) J. Biol. Chem. 277, 11362-11367.
15. Marquez, J. A., Hasenbein, S., Koch, B., Fieulaine, S., Nessler, S., Russell, R. B., Hengstenberg, W. & Scheffzek, K. (2002) Proc. Natl. Acad. Sci. USA 99, 3458-3463.
16. Galinier, A., Kravanja, M., Engelmann, R., Hengstenberg, W., Kilhoffer, M. C., Deutscher, J. & Haiech, J. (1998) Proc. Natl. Acad. Sci. USA 95, 1823-1828.
17. Otwinowski, Z. & Minor, W. (1997) Methods Enzymol. 276, 307-326.
18. Navaza, J. (1994) Acta Crystallogr. A 50, 157-163.
19. Liao, D. I. & Herzberg, O. (1994) Structure (London) 2, 1203-1216.
20. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., et al. (1998) Acta Crystallogr. D 54, 905-921.
21. Lee, B. & Richards, F. M. (1971) J. Mol. Biol. 55, 379-400.
22. Lo Conte, L., Chothia, C. & Janin, J. (1999) J. Mol. Biol. 285, 2177-2198.
23. Wang, G., Sondej, M., Garrett, D. S., Peterkofsky, A. & Clore, G. M. (2000) J. Biol. Chem. 275, 16401-16403.
24. Jones, B. E., Dossonet, V., Küster, E., Hillen, W., Deutscher, J. & Klevit, R. E. (1997) J. Biol. Chem. 272, 26530-26535.
25. Jia, Z., Quail, J. W., Delbaere, L. T. & Waygood, E. B. (1994) Biochem. Cell Biol. 72, 202-217.
26. Reizer, J., Novotny, M. J., Hengstenberg, W. & Saier, M. H., Jr. (1984) J. Bacteriol. 160, 333-340.
27. Zhu, P. P., Herzberg, O. & Peterkofsky, A. (1998) Biochemistry 37, 11762-11770.
28. Audette, G. F., Engelmann, R., Hengstenberg, W., Deutscher, J., Hayakawa, K., Quail, J. W. & Delbaere, L. T. (2000) J. Mol. Biol. 303, 545-553.
29. Deutscher, J., Kessler, U. & Hengstenberg, W. (1985) J. Bacteriol. 163, 1203-1209.
30. Matte, A., Tari, L. W., Goldie, H. & Delbaere, L. T. (1997) J. Biol. Chem. 272, 8105-8108.
31. Sudom, A. M., Prasad, L., Goldie, H. & Delbaere, L. T. (2001) J. Mol. Biol. 314, 83-92.
32. Tari, L., Matte, A., Goldie, H. & Delbaere, L. T. J. (1997) Nat. Struct. Biol. 4, 990-994.
33. Zhou, J. & Adams, J. A. (1997) Biochemistry 36, 2977-2984.
34. Madhusudan, M., Trafny, E. A., Xuong, N. H., Adams, J. A., Ten Eyck, L. F., Taylor, S. S. & Sowadski, J. M. (1994) Protein Sci. 3, 176-187.
35. Johnson, D. A., Akamine, P., Radzio-Andzelm, E., Madhusudan, M. & Taylor, S. S. (2001) Chem. Rev. (Washington, D.C.) 101, 2243-2270.