An alternative derivation of the binding equation for multivalent ligands

Analytical Biochemistry

Volumn 308, Issue 2, 2002, Pages 409-410

  Winzor, Donald J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY;

MULTIVALENT LIGANDS;

CHEMISTRY;

AFFINITY CHROMATOGRAPHY; ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; LIGAND BINDING; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL; STOICHIOMETRY; THEORY;

EID: 0037108813     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(02)00259-2     Document Type: Article

References (7)

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2. G. Scatchard, The attraction of proteins for small molecules and ions, Ann. N. Y. Acad. Sci. 51 (1949) 660-662.
3. L.W. Nichol, L.D. Ward, D.J. Winzor, Multivalency of the partitioning species in quantitative affinity chromatography: evaluation of the site-binding constant for the aldolase-phosphate interaction from studies with cellulose phosphate as the affinity matrix, Biochemistry 20 (1981) 4856-4860.
4. P.J. Hogg, D.J. Winzor, Quantitative affinity chromatography: further developments in the analysis of experimental results from column chromatographic and partition equilibrium experiments, Arch. Biochem. Biophys 234 (1984) 55-63.
5. P.J. Hogg, D.J. Winzor, Effects of ligand multivalency in binding studies: a general counterpart of the Scatchard analysis, Biochim. Biophys. Acta 843 (1985) 59-63.
6. P.J. Flory, Molecular size distribution in three-dimensional polymers. 1. Gelation, J. Am. Chem. Soc. 63 (1941) 3083-3090.
7. S.J. Harris, C.M. Jackson, D.J. Winzor, The rectangular hyperbolic binding equation for multivalent ligands, Arch. Biochem. Biophys. 316 (1995) 20-23.