Hypercapnia and ventilatory periodicity in obstructive sleep apnea syndrome

American Journal of Respiratory and Critical Care Medicine

Volumn 166, Issue 8, 2002, Pages 1112-1115

  Ayappa, Indu ^a,b,c   Berger, Kenneth I ^a,b   Norman, Robert G ^a,b   Oppenheimer, Beno W ^a,b   Rapoport, David M ^a,b   Goldring, Roberta M ^a,b  

^a Division of Pulmonary Critical Care and Sleep Medicine   (United States)

^b BELLEVUE HOSPITAL CENTER   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Carbon dioxide; Hypercapnia (physiopathology); Obesity; Obstructive (physiopathology); Pickwickian syndrome; Sleep apnea

Indexed keywords

CARBON DIOXIDE;

ADULT; AGED; ARTICLE; CARBON DIOXIDE TENSION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HYPERCAPNIA; LUNG VENTILATION; MALE; OBESITY; OBESITY HYPOVENTILATION SYNDROME; PATHOPHYSIOLOGY; PERIODICITY; POLYSOMNOGRAPHY; PRIORITY JOURNAL; SLEEP APNEA SYNDROME; BLOOD; BREATHING; MIDDLE AGED;

ADULT; AGED; CARBON DIOXIDE; FEMALE; HUMANS; HYPERCAPNIA; MALE; MIDDLE AGED; OBESITY; OBESITY HYPOVENTILATION SYNDROME; POLYSOMNOGRAPHY; RESPIRATION; SLEEP APNEA, OBSTRUCTIVE;

EID: 0037108540     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200203-212OC     Document Type: Article

References (18)

1. Resta O, Foschino-Barbaro MP, Bonfitto P, Talamo S, Legari G, De Pergola G, Minenna A, Giorgino R. Prevalence and mechanisms of diurnal hypercapnia in a sample of morbidly obese subjects with obstructive sleep apnoea. Respir Med 2000;94:240-246.
2. Rapoport DM, Garay SM, Epstein H, Goldring RM. Hypercapnia in the obstructive sleep apnea syndrome: a reevaluation of the "Pickwickian syndrome." Chest 1986;89:627-635.
3. Berthon-Jones M, Sullivan CE. Time course of change in ventilatory response to CO2 with long-term CPAP therapy for obstructive sleep apnea. Am Rev Respir Dis 1987;135:144-147.
4. Verin E, Tardif C, Pasquis P. Prevalence of daytime hypercapnia or hypoxia in patients with OSAS and normal lung function. Respir Med 2001;95:693-696.
5. Garay SM, Rapoport D, Sorkin B, Epstein H, Feinberg I, Goldring RM. Regulation of ventilation in the obstructive sleep apnea syndrome. Am Rev Respir Dis 1981;124:451-457.
6. Berger KI, Ayappa I, Chatr-aryamontri B, Marfatia A, Sorkin IB, Rapoport DM, Goldring RM. Obesity hypoventilation syndrome as a spectrum of respiratory disturbances during sleep. Chest 2001;120:1231-1238.
7. Berger KI, Ayappa I, Sorkin IB, Norman RG, Rapoport DM, Goldring RM. CO2 homeostasis during periodic breathing in obstructive sleep apnea. J Appl Physiol 2000;88:257-264.
8. Norman RG, Ahmed MM, Walsleben JA, Rapoport DM. Detection of respiratory events during NPSG: nasal cannula/pressure sensor versus thermistor. Sleep 1997;20:1175-1184.
9. Rechtschaffen A, Kales A. A manual of standardized terminology, techniques, and scoring system for sleep states of human subjects. Washington, DC: U.S. Government Printing Office; 1968. NIH Publication No. 204.
10. Berger KI, Ayappa I, Sorkin IB, Norman RG, Rapoport DM, Goldring RM. Post-event ventilation as a function of CO2 load during respiratory events in obstructive sleep apnea. J Appl Physiol 2002;93:917-924.
11. Greenberg HE, Rapoport DM, Rothenberg SA, Kanengiser LA, Norman RG, Goldring RM. Endogenous opiates modulate the postapnea ventilatory response in the obstructive sleep apnea syndrome. Am Rev Respir Dis 1991;143:1282-1287.
12. Gislason T, Almqvist M, Boman G, Lindholm CE, Terenius L. Increased CSF opioid activity in sleep apnea syndrome: regression after successful treatment. Chest 1989;96:250-254.
13. Orlowski JP, Herrell DW, Moodie DS. Narcotic antagonist therapy of the obesity hypoventilation syndrome. Crit Care Med 1982;10:604-607.
14. Ferber C, Duclaux R, Mouret J. Naltrexone improves blood gas patterns in obstructive sleep apnoea syndrome through its influence on sleep. J Sleep Res 1993;2:149-155.
15. Han F, Chen E, Wei H, He Q, Ding D, Strohl KP. Treatment effects on carbon dioxide retention in patients with obstructive sleep apnea-hypopnea syndrome. Chest 2001;119:1814-1819.
16. Bradley TD, Rutherford R, Lue F, Moldofsky H, Grossman, RF, Zamel N, Phillipson EA. Role of diffuse airway obstruction in the hypercapnia of obstructive sleep apnea. Am Rev Respir Dis 1986;134:920-924.
17. Javaheri S, Colangelo G, Lacey W, Gartside PS. Chronic hypercapnia in obstructive sleep apnea-hypopnea syndrome. Sleep 1994;17:416-423.
18. Resta O, Foschino BM, Bonfitto P, Talamo S, Mastrosimone V, Stefano A, Giliberti T. Hypercapnia in obstructive sleep apnoea syndrome. Neth J Med 2000;56:215-222.