A single FKS homologue in Yarrowia lipolytica is essential for viability

Yeast

Volumn 19, Issue 12, 2002, Pages 1003-1014

  León, Maela ^a   Sentandreu, Rafael ^a   Zueco, Jesús ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Cell wall; FKS1; Glucan synthase; Yarrowia lipolytica

Indexed keywords

AMINO ACID; BETA 1,3 GLUCAN; GLUCAN SYNTHASE; GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; OLIGONUCLEOTIDE; PROTEIN FKS1; RHO FACTOR; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; ASPERGILLUS NIDULANS; CANDIDA ALBICANS; CARBOHYDRATE SYNTHESIS; CELL MEMBRANE; CELL SHAPE; CELL STRUCTURE; CELL VIABILITY; CELL WALL; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; ENZYME ACTIVE SITE; ENZYME SUBUNIT; FUNGUS GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PARACOCCIDIOIDES BRASILIENSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN ISOLATION; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; SEQUENCE HOMOLOGY; SPECIES DIFFERENTIATION; YARROWIA LIPOLYTICA; YEAST CELL;

AMINO ACID SEQUENCE; CELL WALL; FUNGAL PROTEINS; GENES, ESSENTIAL; GENES, FUNGAL; GLUCANS; GLUCOSYLTRANSFERASES; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PROTOPLASTS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; YARROWIA;

ASPERGILLUS; CANDIDA; CANDIDA ALBICANS; EMERICELLA NIDULANS; FILOBASIDIELLA NEOFORMANS; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE; YARROWIA LIPOLYTICA;

EID: 0037105489     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/yea.893     Document Type: Article

References (21)

1. Yarrowia lipolytica
2. The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-β-D-glucan synthase
3. Rho1p, a yeast protein at the interphase between cell polarization and morphogenesis
4. New yeast-Escherichia coli shuttle vector constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
5. MHY1 encodes a C2H2-type zinc finger protein that promotes dimorphic transition in the yeast Yarrowia lipolytica
6. A rac homologue is required for induction of hyphal growth in the dimorphic yeast Yarrowia lipolytica
7. cps1, a Schizosaccharomyces pombe gene homologue of Saccharomyces cerevisiae FKS genes whose mutation confers hypersensitivity to cyclosporin A and papulacandin B
8. Transformation of intact yeast cells treated with alkali cations
9. Isolation of a gene involved in 1,3-β-glucan synthesis in Aspergillus nidulans and purification of the corresponding protein
10. Identification of the uridine 5′-diphosphoglucose (UDP-Glc) binding subunit of cellulose synthase in Acetobacter xylinum using the photoaffinity probe 5-azido-UDP-Glc
11. A phosphatidylinositol/phosphatidylcholine transfer protein is required for differentiation of the dimorphic yeast Yarrowia lipolytica form yeast to the mycelial form
12. bgs2, a sporulation-specific glucan synthase homologue is required for proper ascospore wall maturation in fission yeast
13. Differential expression and function of two homologous subunits of yeast 1,3-β-D-glucan synthase
14. In vitro activity of 1,3-β-D-glucan synthase requires the GTP-binding protein Rho1
15. Cloning of the Candida albicans homologue of Saccharomyces cerevisiae GSC1/FKS1 and its involvement in β-1,3-glucan synthesis
16. Molecular cloning and characterization of a glucan synthase gene from the human pathogenic fungus Paracoccidioides brasiliensis
17. Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-β-glucan synthase
18. Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast
19. A glucan synthase FKS1 homologue in Cryptococcus neoformans is single copy and encodes an essential function
20. Temperature-induced expression of yeast FKS2 is under the dual control of protein kinase C and calcineurin