The nitration of proteins in platelets: Significance in platelet function

Free Radical Biology and Medicine

Volumn 33, Issue 6, 2002, Pages 728-736

  Sabetkar, Mojhgan ^a   Low, Sylvia Y ^a   Naseem, Khalid M ^b   Bruckdorfer, K Richard ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

Free radicals; Hydrogen peroxide; Nitric oxide; Peroxynitrite; Tyrosine nitration; Vasodilator sensitive phosphoprotein

Indexed keywords

COLLAGEN; HYDROGEN PEROXIDE; PEROXYNITRITE; PROTEIN; REACTIVE OXYGEN METABOLITE; TYROSINE;

CELL ACTIVITY; CELL ISOLATION; CELL STIMULATION; CYTOLOGY; EXPOSURE; NITRATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE FUNCTION;

EID: 0037105338     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00890-0     Document Type: Article

References (56)

1. Radomski M.W., Palmer R.M., Moncada S. Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium. Lancet. 2:1987;1057-1058.
2. Radomski M.W., Palmer R.M., Moncada S. The role of nitric oxide and cyclic GMP in platelet adhesion to vascular endothelium. Biochem. Biophys. Res. Commun. 148:1987;1482-1489.
3. Radomski M.W., Palmer R.M.J., Moncada S. The antiaggregating properties of vascular endothelium interactions between prostacyclin and nitric oxide . Br. J. Pharmacol. 92:1987;639-646.
4. Radomski M.W., Palmer R.M.J., Moncada S. Characterization of the L-arginine nitric oxide pathway in human platelets . Br. J. Pharmacol. 101:1990;325-328.
5. Freedman J.E., Loscalzo J., Barnard M.R., Alpert C., Keaney J.F., Michelson A.D. Nitric oxide released from activated platelets inhibits platelet recruitment. J. Clin. Invest. 100:1997;350-356.
6. Maresca M., Colao C., Leoncini G. Generation of hydrogen peroxide in resting and activated platelets. Cell Biochem. Funct. 10:1992;79-85.
7. Practico D., Iuliano L., Pulcinelli F.M., Bonavita M.S., Gazzaniga P.P., Violi F. Hydrogen peroxide triggers activation of human platelets selectively exposed to non- aggregating concentrations of arachidonic acid and collagen. J. Lab. Clin. Med. 119:1992;364-370.
8. Canoso R.T., Rodvien R., Scoon K., Levine H. Hydrogen peroxide and platelet function. Blood. 43:1974;645-656.
9. Stuart M.J., Holmsen H. Hydrogen peroxide an inhibitor of platelet function effect ion adenine nucleotide metabolism, and the release reaction . Am. J. Hematol. 2:1977;53-63.
10. Naseem K.M., Bruckdorfer K.R. Hydrogen peroxide at low concentrations strongly enhanced the inhibitory effect of nitric oxide on platelets. Biochem. J. 310:1995;149-153.
11. Naseem K.M., Chirico S., Mohammadi B., Bruckdorfer K.R. The synergism of hydrogen peroxide with plasma S-nitrosothiols in the inhibition of platelet activation. Biochem. J. 318:1996;759-766.
12. Naseem K.M., Bruckdorfer K.R. The influence of organic peroxides on platelet aggregation and sensitivity to nitric oxide. Platelets. 10:1999;146-152.
13. Matoba T., Shimokawa H., Nakashima M., Hirakawa Y., Mukai M., Hirano K., Kanaide H., Takshita A. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice. J. Clin. Invest. 106:2000;1521-1530.
14. Kooy N.W., Royal J.A. Agonist-induced peroxynitrite production from endothelial cells. Arch. Biochem. Biophys. 310:1994;352-359.
15. Moro M.A., Darley-Usmar V., Goodwin D.A., Read R.G., Zamora-Pino R., Feelisch M., Radomski M.W., Moncada S. Paradoxical fate and biological action of peroxynitrite on human platelets. Proc. Natl. Acad. Sci. USA. 91:1994;6702-6706.
16. Brown A.S., Moro M.A., Masse J.M., Cramer E.M., Radomski M., Darley-Usmar V. Nitric oxide-dependent and independent effects on human platelets treated with peroxynitrite. Cardiovasc. Res. 40:1998;380-388.
17. Boulos C., Jiang H., Balazy M. Diffusion of peroxynitrite into the human platelet inhibits cyclo-oxygenase via nitration of tyrosine residues. J. Pharmacol. Exp. Ther. 293:2000;222-229.
18. Mayer B., Schrammel A., Klatt P., Koesling D., Schmidt K. Peroxynitrite-induced accumulation of cyclic GMP in endothelial cells and stimulated soluble guanylyl cyclase. Dependence on glutathione and possible role of S-nitrosylation. J. Biol. Chem. 270:1995;17355-17360.
19. Low S.Y., Sabetkar M., Bruckdorfer K.R., Naseem K.M. The role of protein nitration in the inhibition of platelet activation by peroxynitrite. FEBS Lett. 511:2002;59-64.
20. Sabetkar M., Naseem K.M., Tullet J.M., Friebe A., Koesling D., Bruckdorfer K.R. Synergism between nitric oxide and hydrogen peroxide in the inhibition of platelet function the roles of soluble guanylyl cyclase and vasodilator-stimulated phosphoprotein . Nitric Oxide. 3:2001;233-242.
21. Mandoro T.H., Shafer B.C., Vostal J.G. Peroxynitrite-induced tyrosine nitration and phosphorylation in human platelets. Free Radic. Biol. Med. 22:1997;1055-1063.
22. Naseem K.M., Low S.Y., Sabetkar M., Bradley N.J., Khan J., Jacobs M., Bruckdorfer K.R. The nitration of platelet cytosolic proteins during agonist-induced activation of platelets. FEBS Lett. 473:2000;119-122.
23. Halbrugge M., Friedrich C., Eigenthaler M., Schanzenbacher P., Walter U. Stoichiometric and reversible phosphorylation of 46 kDa protein in human platelets in response to cGMP and cAMP elevation. J. Biol. Chem. 286:1990;3088-3093.
24. Nolte C., Eigentaler M., Horstrup K., Honig-Liedl P., Walter U. Synergistic phosphorylation of the focal adhesion-associated vasodilator-stimulated phosphoprotein in intact human platelets in response to cGMP- and cAMP elevating platelets inhibitors. Biochem. Pharmacol. 48:1994;1569-1575.
25. Vargas J.R., Radomski M.W., Moncada S. The use of prostacyclin in the separation from plasma and washing of human platelets. Prostaglandins. 23:1982;921-945.
26. Lagarde M., Byron P.A., Guichardant M., Dervachanne M. A simple and efficient method for platelet isolation from the plasma. Thromb. Res. 17:1980;581-588.
27. Pannala A.S., Rice-Evans C.A., Halliwell B., Singh S. Inhibition of peroxynitrite- mediated nitration by catechin polyphenols. Biochem. Biophys. Res. Commun. 232:1997;164-168.
28. Schroeder P., Klotz L.-A., Buschzyk D.P., Sadik C.D., Schewe T., Sies H. Epicatechin selectively prevents nitration but not oxidation reactions of peroxynitrite. Biochem. Biophys. Res. Commun. 285:2001;782-787.
29. Oury T.D., Tatro L., Ghio A.J., Piantadosi C.A. Nitration of tyrosine by hydrogen peroxide and nitrite. Free Radic. Res. 23:1995;537-547.
30. Sampson J.B., Ye Y., Rosen H., Beckman J.S. Myeloperoxidase and horseradish peroxidase catalyze tyrosine nitration in proteins from nitrite and hydrogen peroxide. Arch. Biochem. Biophys. 356:1998;207-213.
31. Kilinc K., Kilinc A., Wolf R.E., Grisham M.B. Myoglobin-catalysed tyrosine nitration no need for peroxynitrite . Biochem. Biophys. Res. Commun. 285:2001;273-276.
32. Banan A., Fields J.Z., Zhang Y., Kheshavarzian A. iNOS upregulation mediates oxidant-induced disruption of F-actin an barrier function of intestinal monolayers. Am. J. Physiol. 280:2001;G1234-G1246.
33. Sabetkar M., Low S.Y., Naseem K.M., Bruckdorfer K.R. The nitration of specific platelet proteins and its disappearance during handling of platelets. Platelets. 12:2001;53.
34. McBride A.G., Borutaite V., Brown G. Superoxide dismutase and hydrogen peroxide cause rapid nitric oxide breakdown, peroxynitrite production and subsequent cell death. Biochim. Biophys. Acta. 1454:1999;275-288.
35. Brunelli L., Yermilov V., Beckman J.S. Modulation of catalase peroxidatic and catalatic activity by nitric oxide. Free Radic. Biol. Med. 30:2001;709-714.
36. Abu-Soud H.M., Hazen S.L. Nitric oxide is a physiological substrate for mammalian peroxidases. J. Biol. Chem. 275:2000;37524-37532.
37. Alvarez B., Radi R. Peroxynitrite decay in the presence of hydrogen peroxide, mannitol and ethanol a reappraisal . Free Radic. Res. 34:2001;467-475.
38. Gunther M.R., Hsi L.C., Curtis J.F., Gierse J.K., Marnett L.J., Eling T.E., Mason R.P. Nitric oxide trapping of the tyrosyl radical of prostaglandin H synthase-2 leads to tyrosine iminoxyl radical and nitrotyrosine formation. J. Biol. Chem. 272:1997;17086-17090.
39. O'Donnell V.B., Taylor K.B., Parthasarathy S., Kuhn H., Koesling D., Friebe A., Bloodsworth A., Darley-Usmar V.M., Freeman B.A. 15-Lipoxygenase catalytically consumes nitric oxide and impairs the activation of guanylyl cyclase. J. Biol. Chem. 274:1999;20083-20091.
40. Fujimoto Y., Tagano S., Ogawa K., Sakuma S., Fujita T. Comparison of the effects of nitric oxide and peroxynitrite on the 12-lipoxygenase and cyclo-oxgenase metabolism of arachidonic acid in rabbit platelets. Prostaglandins Leukot. Essent. Fatty Acids. 59:1998;95-100.
41. Amirmansour C., Vallance P., Bogle R.G. Tyrosine nitration in blood vessels occurs with increasing nitric oxide concentrations. Br. J. Pharmacol. 127:1999;788-794.
42. Gow A.J., Duran D., Malcolm S., Ischiropoulos H. Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation. FEBS Lett. 385:1996;63-66.
43. Takakura K., Beckmann J.S., MacMillan-Crow L.A., Crow J.P. Rapid and irreversible inactivation of protein tyrosine phosphatases PTP1B, CD45 and LAR by peroxynitrite. Arch. Biochem. Biophys. 369:1999;197-207.
44. 2 peptide . Proc. Natl. Acad. Sci. USA. 93:1996;3377-3382.
45. Kamisaki Y., Wada K., Bian K., Balabanli B., Davis K., Martin E., Behbod F., Lee Y.-C., Murad F. An activity in rat tissues that modifies nitrotyrosine-containing proteins. Proc. Natl. Acad. Sci. USA. 95:1998;11584-11589.
46. Balabanli B., Kamisaki Y., Martin E., Murad F. Requirements for heme and thiols for the non-enzymatic modifications of nitrotyrosine. Proc. Natl. Acad. Sci. USA. 96:1999;13136-13141.
47. Gillette J.R. Significance of mixed oxygenases and nitroreductase in drug metabolism. Ann. N.Y. Acad. Sci. 160:1969;558-570.
48. Kuo W.-N., Kanadia R.N., Shanbag V.P., Toro R. Denitration of peroxynitrate-treated proteins by "protein nitrases" from rat brain and heart. Mol. Cell. Biochem. 201:1999;11-66.
49. 2 -terminal kinase. Am. J. Physiol. 277:1999;H1647-H1653.
50. Zou M.-H., Leist M., Ullrich V. Selective nitration of prostacyclin synthase and defective vasorelaxation in atherosclerotic bovine coronary arteries. Am. J. Pathol. 154:1999;1359-1365.
51. Klotz L.-O., Schieke M., Sies H., Holbrook N.J. Peroxynitrite activates the phosphoinositide 3- kinase/Akt pathway in human skin primary fibroblasts. Biochem. J. 352:2000;219-225.
52. Mallozzi C., Di Stasi A.M., Minnetti M. Nitrotyrosine mimics the phosphotyrosine binding to the SH2 domain of the src family tyrosine kinase lyn. FEBS Lett. 503:2001;189-195.
53. Gross B.S., Lee J.R., Clements J.L., Turner M., Tybulewicz V.L., Findell P.R., Koretzky G.A., Watson S.P. Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets. J. Biol. Chem. 274:1999;5963-5971.
54. Aulak K.S., Miyagi M., Yan L., West K.A., Massillon D., Crabb J.W., Stuehr D. Proteomic method identifies proteins nitrated in vivo during inflammatory challenge. Proc. Natl. Acad. Sci. USA. 98:2001;12056-12061.
55. Berlett B.S., Friguet B., Yim M.B., Chock P.B., Stadtman E.R. Peroxynitrite- mediated nitration of tyrosine residues in Escherischia coli glutamine synthetase mimics adenylylation relevance to signal transduction . Proc. Natl. Acad. Sci. USA. 93:1996;1776-1780.
56. Herrero M.B., de Lamirande E., Gagnon C. Tyrosine nitration in human spermatozoa a physiological function of peroxynitrite, the reaction product of nitric oxide and superoxide . Mol. Hum. Reprod. 7:2001;913-921.