A novel simple method for the investigation of drug binding to the KATP channel sulfonylurea receptor

Analytical Biochemistry

Volumn 307, Issue 2, 2002, Pages 383-385

  Mikhailova, Ellina A ^a   Ashcroft, Stephen J H ^a   Mikhailov, Michael V ^a,b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY;

DRUG BINDING; SIMPLE METHOD; SULFONYLUREA RECEPTORS;

CHEMISTRY;

ADENOSINE TRIPHOSPHATE; GLIBENCLAMIDE; GLICLAZIDE; POTASSIUM CHANNEL; REPAGLINIDE; SULFONYLUREA; SULFONYLUREA RECEPTOR; TOLBUTAMIDE;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; DRUG RECEPTOR BINDING; DRUG TARGETING; GLUCOSE BLOOD LEVEL; INSULIN RELEASE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0037102324     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(02)00032-5     Document Type: Article

References (15)

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2. Familial persistent hyperinsulinemic hypoglycemia of infancy and mutations in the sulfonyurea receptor
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4. Cloning of the beta cell high-affinity sulfonylurea receptor: A regulator of insulin secretion
5. Reconstitution of IKATP: An inward rectifier subunit plus the sulfonylurea receptor
6. Properties and functions of ATP-sensitive K-channels
7. Tissue specificity of sulfonylureas - Studies on cloned cardiac and beta-cell KATP channels
8. Investigation of the molecular assembly of b-cell KATP channels
9. Pancreatic b-cell KATP channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide
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11. ATP channels
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