Expression of the leucocyte common antigen-related (LAR) tyrosine phosphatase is regulated by cell density through functional E-cadherin complexes

Biochemical Journal

Volumn 365, Issue 2, 2002, Pages 513-519

  Symons, Javelle R ^a   Levea, Charles M ^a   Mooney, Robert A ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

catenin; MCF 7

Indexed keywords

ANTIBODIES; BIOLOGICAL ORGANS; CALCIUM; CHELATION; GENES; PHOSPHATES; SUBSTRATES; TUMORS;

ANTIGENS;

ANTIBODY; CD45 ANTIGEN; LEUKOCYTE COMMON ANTIGEN RELATED PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG; UVOMORULIN; UVOMORULIN ANTIBODY;

ANIMAL CELL; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL CULTURE; CELL COMMUNICATION; CELL DENSITY; CELL JUNCTION; CELL STRAIN COS7; CELL STRAIN MCF 7; CELL SURFACE; COMPLEX FORMATION; CONTACT INHIBITION; CONTROLLED STUDY; ENZYME SUBSTRATE; EXTRACELLULAR CALCIUM; GENE EXPRESSION REGULATION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DETERMINATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CADHERINS; COS CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; KINETICS; NERVE TISSUE PROTEINS; PROTEIN-TYROSINE-PHOSPHATASE; RATS; RECEPTORS, CELL SURFACE; TUMOR CELLS, CULTURED;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS;

EID: 0037101783     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020381     Document Type: Article

References (37)

1. Gumbiner, B. M. (1996) Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84, 345-357
2. Vleminckx, K. and Kemler, R. (1999) Cadherins and tissue formation: integrating adhesion and signaling. Bioessays 21, 211-220
3. Nagafuchi, A., Ishihara, S. and Tsukita, S. (1994) The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-α catenin fusion molecules. J. Cell. Biol. 127, 235-245
4. Mareel, M., Bracke, M. and van Roy, F. (1994) Invasion promoter versus invasion suppressor molecules: the paradigm of E-cadherin. Mol. Biol. Rep. 19, 45-67
5. Shiozaki, H., Oka, H., Inoue, M., Tamura, S. and Monden, M. (1996) E-cadherin mediated adhesion system in cancer cells. Cancer 77, 1605-1613
6. Bukholm, I. K., Nesland, J. M., Karesen, R., Jacobsen, U. and Borresen-Dale, A. L. (1998) E-cadherin and alpha-, beta-, and gamma-catenin protein expression in relation to metastasis in human breast carcinoma. J. Pathol. 185, 262-266
7. Kanner, S. B., Reynolds, A. B. and Parsons, J. T. (1991) Tyrosine phosphorylation of a 120 kD pp60src substrate upon EGF and PDGF receptor stimulation and in polyomavirus middle T-antigen transformed cells. Mol. Cell. Biol. 11, 713-720
8. Xu, Y. and Carpenter, G. (1999) Identification of cadherin tyrosine residues that are phosphorylated and mediate Shc association. J. Cell Biochem. 75, 264-271
9. Hinck, L., Nathke, I., Papkoff, J. and Nelsen, W. J. (1994) β-catenin: a common target for the regulation of cell adhesion by Wnt-1 and Src signaling pathways. Trends Biochem. Sci. 19, 538-542
10. Papkoff, J. (1997) Regulation of complexed and free catenin pools by distinct mechanisms: differential effects of Wnt-1 and v-Src. J. Biol. Chem. 272, 4536-4543
11. Takahashi, K., Suzuki, K. and Tsukatani, Y. (1997) Induction of tyrosine phosphorylation and association of β-catenin with EGF receptor upon tryptic digestion of quiescent cells at confluence. Oncogene 15, 71-78
12. Shibata, T., Ochiai, A., Kanai, Y., Akimoto, S., Gotoh, M., Yasui, N., Machinami, R. and Hirohashi, S. (1996) Dominant negative inhibition of the association between β-catenin and c-erbB-2 by N-terminally deleted β-catenin suppresses the invasion and metastasis of cancer cells. Oncogene 13, 883-889
13. Hiscox, S. and Jiang, W. G. (1999) Association of the HGF/SF receptor, c-met, with the cell-surlace adhesion molecule, E-cadherin, and catenins in human tumor cells. Biochem. Biophys. Res. Commun. 261, 406-411
14. Hiscox, S. and Jiang, W. G. (1999) Hepatocyte growth factor/scatter factor disrupts epithelial tumour cell-cell adhesion: involvement of beta-catenin. Anticancer Res. 19, 509-517
15. Rahim, N., Hung, W., Tremblay, E., Sualnier, R. and Elliott, B. (1998) c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammmary carcinoma cells. J. Biol. Chem. 273, 33714-33721
16. Matsuyoshi, N., Hamaguchi, M., Taniguchi, S., Nagafuchi, A., Tsukita, S. and Takeichi, M. (1992) Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J. Cell Biol. 118, 703-714
17. Kypta, R. M., Su, H. and Reichardt, L. F. (1996) Association between a transmembrane protein tyrosine phosphatase and the cadherin-catenin complex. J. Cell. Biol. 134, 1519-1529
18. Brady-Kalnay, S. M., Rimm, D. L. and Tonks, N. K. (1995) Receptor protein tyrosine phosphatase PTPμ associates with cadherins and catenins in vivo. J. Cell Biol. 130, 977-986
19. Balsamo, J., Leung, T., Ernst, H., Zanin, M., Hoffman, S. and Lilien, J. (1996) Regulated binding of a PTP1B-like phosphatase to N-cadherin: control of cadherin-mediated adhesion by dephosphorylation of β-catenin. J. Cell. Biol. 134, 801-813
20. Keilhack, H., Hellman, U., van Henget, J., van Roy, F., Godovac-Zimmermann, J. and Bohmer, F. D. (2000) The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 catenin. J. Biol. Chem. 275, 26376-26384
21. Ukropec, J. A., Hollinger, M. K., Salva, S. M. and Woolkalis, M. J. (2000) SHP2 association with VE-cadherin complexes in human endothelial cells is regulated by thrombin. J. Biol. Chem. 275, 5983-5986
22. Ozawa, M. and Kemler, R. (1998) Altered cell adhesion activity by pervanadate due to the dissociation of α-catenin from the E-cadherin-catenin complex. J. Biol. Chem. 273, 6166-6170
23. Muller, T., Choidas, A., Reichmann, E. and Ullrich, A. (1999) Phosphorylation and free pool of β-catenin are regulated by tyrosine kinases and tyrosine phosphatase during epithelial cell migration. J. Biol. Chem. 274, 10173-10183
24. Bleyle, L. A., Peng, Y., Ellis, C. and Mooney, R. A. (1999) Dissociatioin of PTPase levels from their modulation of insulin receptor signal transduction. Cell Signal. 11, 719-725
25. Nose, A., Nagafuchi, A. and Takeichi, M. (1988) Expressed recombinant cadherins mediate cell sorting in model systems. Cell 54, 993-1001
26. Aicher, B., Lerch, M. M. Muller, T., Schilling, J. and Ullrich, A. (1997) Cellular redistribution of protein tyrosine phosphatases LAR and PTPσ by inducible proteolytic processing. J. Cell Biol. 138, 681-696
27. Schaapveld, R., Schepens, J., Robinson, G., Attema, J., Oerlemans, F., Fransen, J., Streuli, M., Wieringa, B., Hennighausen, L. and Hendriks, W. (1997) Impaired mammary gland development and function in mice lacking LAR receptor-like tyrosine phosphatase activity. Dev. Biol. 188, 134-146
28. Neri, A., Welch, D., Kawaguchi, T. and Nicolson, G. L. (1982) Development and biological properties of malignant cell sublines and clones of a spontaneously metastasizing rat mammary adnocarcinoma. J. Natl. Cancer Inst. 68, 507-517
29. Gebbink, M. F. B. G. Zondag, G. C. M., Koningstein, G. M., Feiken, E., Wubbolts, R. W. and Moolenaar, W. H. (1995) Cell surface expression of receptor protein tyrosine phosphatase RPTPμ is regulated by cell-cell contact. J. Cell Biol. 131, 251-260
30. Zhang, J. S., Honkaniemi, J., Yang, T., Yeo, T. T. and Longo, F. M. (1998) LAR tyrosine phosphatase receptor: A developmental isoform is present in neurites and growth cones and its expression is regional- and cell-specific. Mol. Cell Neurosci. 10, 271-286
31. Zhai, Y., Wirth, J., Kang, S., Welsch, C. W. and Esselman, W. J. (1995) LAR-PTPase cDNA transfection suppression of tumor growth of neu oncogen-transformed human breast carcinoma cells. Mol. Carcinogen. 14, 103-110
32. Weng, L.-P., Yuan, J. and Yu, Q. (1998) Overexpression of the transmembrane tyrosine phosphatase LAR activates the caspase pathway and induces apoptosis. Curr. Biol. 8, 247-256
33. Lambert, M., Padilla, F. and Mege, R. M. (2000) Immobilized dimers of N-cadherin-Fc chimera mimic cadherin-mediated cell contact formation: contribution of both outside-in and inside-out signals. J. Cell Sci. 113, 2207-2219
34. Ostman, A., Yang, O. and Tonks, N. K. (1994) Expression of DEP-1, a receptor-like PTP, is enhanced with increasing cell density. Proc. Natl. Acad. Sci. U.S.A. 91, 9680-9684
35. O'Grady, P., Thai, T. C. and Saito, H. (1998) The laminin-nidogen complex is a ligand for a specific splice isoform of the transmembrane protein tyrosine phosphatase LAR. J. Cell Biol. 141, 1675-1684
36. Behrens, J., Vakaet, L., Friis, R., Winterhager, E., van Roy, F., Marcel, M. M. and Birchmeier, W. (1993) Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J. Cell Biol. 120, 757-766
37. Kinch, M. S., Clark, G. J., Der, C. J. and Burridge, K. (1995) Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia. J. Cell Biol. 130, 461-471