Function of the 90-loop (Thr90-Glu100) region of staphylokinase in plasminogen activation probed through site-directed mutagenesis and loop deletion

Biochemical Journal

Volumn 365, Issue 2, 2002, Pages 379-389

  Rajamohan, Govindan ^a   Dahiya, Monika ^a   Mande, Shekhar C ^a   Dikshit, Kanak L ^a  

^a INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

Author keywords

Kringle domain; Molecular modelling; Site directed mutagenesis

Indexed keywords

ENZYMES; MOLECULAR BIOLOGY; MUTAGENESIS;

PLASMINOGENS;

BIOCHEMISTRY;

ALANINE; LYSINE DERIVATIVE; PLASMINOGEN; STAPHYLOKINASE;

ARTICLE; COMPLEX FORMATION; DELETION MUTANT; DRUG ACTIVITY; DRUG BINDING; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

BASE SEQUENCE; CATALYSIS; DNA PRIMERS; GLUTAMIC ACID; HUMANS; METALLOENDOPEPTIDASES; MODELS, MOLECULAR; MOLECULAR PROBES; MUTAGENESIS, SITE-DIRECTED; PLASMINOGEN; THREONINE;

EID: 0037101775     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20011647     Document Type: Article

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