Physical mobilization of secretory vesicles facilitates neuropeptide release by nerve growth factor-differentiated PC12 cells

Journal of Physiology

Volumn 542, Issue 2, 2002, Pages 395-402

  Ng, Yuen Keng ^a   Lu, Xinghua ^a   Levitan, Edwin S ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BARIUM ION; F ACTIN; GREEN FLUORESCENT PROTEIN; JASPAMIDE; NERVE GROWTH FACTOR; NEUROPEPTIDE; MYCALOLIDE B; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL STRAIN; CONTROLLED STUDY; DENSE BODY; EXOCYTOSIS; FLUORESCENCE ANALYSIS; HYPOTHESIS; NEUROSECRETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; SECRETORY VESICLE; CELL MOTION; DENSE CORE VESICLE; DEPOLARIZATION; DEPOLYMERIZATION; HUMAN; HUMAN CELL; MOBILIZATION; PC12 CELL LINE;

ACTINS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIFFERENTIATION; DEPSIPEPTIDES; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MOVEMENT; NERVE GROWTH FACTOR; NEUROPEPTIDES; OXAZOLES; PC12 CELLS; PEPTIDES, CYCLIC; PHEOCHROMOCYTOMA; RATS; RECOMBINANT PROTEINS; SECRETORY VESICLES;

EID: 0037101566     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2002.021733     Document Type: Article

References (33)

1. ABNEY, J. R., MELIZA, C. D., CUTLER, B., KINGMA, M., LOCHNER, J. E. & SCALETTAR, B. A. (1999). Real-time imaging of the dynamics of secretory granules in growth cones. Biophysical Journal 77, 2887-2895.
2. BETZ, W. J. & HENKEL, A. W. (1994). Okadaic acid disrupts clusters of synaptic vesicles in frog motor nerve terminals. Journal of Cell Biology 124, 843-854.
3. BUBB, M. R., SENDEROWICZ, A. M., SAUSVILLE, E. A., DUNCAN, K. L. & KORN, E. D. (1994). Jasplakinolide, a cytotoxic: natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin. Journal of Biological Chemistry 269, 14869-14871.
4. BURKE, N., HAN, W., LI, D., TAKIMOTO, K., WATKINS, S. C. & LEVITAN, E. S. (1997). Neuronal peptide release is limited by secretory granule mobility. Neuron 19, 1095-1102.
5. CHOWDHURY, H. H., POPOFF, M. R. & ZOREC, R. (1999). Actin cytoskeleton depolymerization with Clostridium spiroforme toxin enhances the secretory activity of rat melanotrophs. Journal of Physiology 521, 389-395.
6. CRAMER, L. P. (1999). Role of actin-filament disassembly in lamellipodium protrusion in motile cells revealed using the drug jasplakinolide. Current Biology 9, 1095-1105.
7. FERNANDEZ-ALFONSO, T., SANKARANARAYANAN, S. & RYAN, T. A. (2001). Barium converts nonrecycling synaptic vesicles to recycling synaptic vesicles in CNS synapses. Society for Neuroscience Abstracts 27, 386.
8. 2+ -induced deprotonation of peptide hormones inside secretory vesicles in preparation for release. Journal of Neuroscience 19, 900-905.
9. HAN, W., NG, Y-K., AXELROD, D. & LEVITAN, E. S. (1999b). Neuropeptide release by efficient recruitment of diffusing cytoplasmic secretory vesicles. Proceedings of the National Academy of Sciences of the USA 96, 14577-14582.
10. HILFIKER, S., PIERBONE, V. A., CZERNIK, A. J., KAO, H.-T., AUGUSTINE, G. J. & GREENGARD, P. (1999). Synapsins as regulators of neurotransmitter release. Philosophical Transactions of the Royal Society B 354, 269-279.
11. HILFIKER S., SCHWEIZER, F. E., KAO, H. T., CZERNIK, A. J., GREENGARD, P. & AUGUSTINE, G. J. (1998). Two sites of action for synapsin domain E in regulating neurotransmitter release. Nature Neuroscience 1, 29-35.
12. KAETHER, C., SALM, T., GLOMBIK, M., ALMERS, W. & GERDES, H. H. (1997). Targeting of green fluorescent protein to neuroendocrine secretory granules: a new tool for real time studies of regulated protein secretion. European Journal of Cell Biology 74, 133-142.
13. KARHUNEN, T., VILIM, F. S., ALEXEEVA, V., WEISS, K. R. & CHURCH, P. J. (2001). Targeting of peptidergic vesicles in cotransmitting terminals. Journal of Neuroscience 21, 1-5.
14. LANG, T., WACKER, I., WUNDERLICH, I., ROHRBACH, A., GIESE, G., SOLDATI, T. & ALMERS, W. (2000). Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells. Biophysical Journal 78, 2863-2877.
15. LEENDERS, A. G., SCHLOTEN, G., WIEGANT, V. M., DA SILVA, F. H. & GHIJSEN, W. E. (1999). Activity-dependent neurotransmitter release kinetics: correlation with changes in morphological distributions of small and large vesicles in central nerve terminals. European Journal of Neuroscience 11, 4269-4277.
16. LEVITAN, E. S. (1998). Studying neuronal peptide release and secretory granule dynamics with GFP. Methods 16, 182-187.
17. LEVITAN, E. S., TULLY, A. & DEITCHER, D. L. (2002). Stimulation induces physical mobilization of neuropeptidergic secretory vesicles in living synapses. Biophysical Journal 82, 279a.
18. MORALES, M., COLICOS, M. A. & GODA, Y. (2000). Actin-dependent regulation of neurotransmitter release at central synapses. Neuron 27, 539-550.
19. NG, Y.-K., LU, X., WATKINS, S. C., ELLIS-DAVIES, G. C. R. & LEVITAN, E. S. (2002). NGF changes the cellular organization of regulated peptide release by PC12 cells. Journal of Neuroscience 22, 3890-3897.
20. OHEIM, M. & STUHMER, W. (2000). Tracking chromaffin granules on their way through the actin cortex. European Biophysics Journal 29, 67-89.
21. RAO, S., LANG, C., LEVITAN, E. S. & DEITCHER, D. L. (2001). Visualization of neuropeptide expression, transport, and exocytosis in Drosophila melanogaster. Journal of Neurobiology 49, 159-172.
22. RAUCHER, D., STAUFFER, T., CHEN, W., SHEN, K., GUO, S., YORK, J. D., SHEETZ, M. P. & MEYER, T. (2000). Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion. Cell 100, 221-228.
23. RUDOLF, R., SALM, T., RUSTOM, A. & GERDES, H. H. (2001). Dynamics of immature secretory granules: role of cytoskeletal elements during transport, cortical restriction, and F-actin-dependent tethering. Molecular and Cellular Biology 12, 1353-1365.
24. SACHS, H., SHARE, L., OSINCHAK, J. & CARPI, A. (1967). Capacity of the neurohypophysis to release vasopressin. Endocrinology 81, 755-770.
25. SAITO, S., WATABE, S., OZAKI, H., FUSETANI, N. & KARAKI, H. (1994). Mycalolide B, a novel actin depolymerizing agent. Journal of Biological Chemistry 269, 29710-29714.
26. TOOZE, S. A., FLATMARK, T., TOOZE, J. & HUTTNER, W. B. (1991). Characterization of the immature secretory granule, an intermediate in granule biogenesis. Journal of Cell Biology 115, 1491-1503.
27. VITALE, M. L., SEWARD, E. P. & TRIFARO, J. M. (1995). Chromaffin cell cortical actin network dynamics control the size of the release-ready vesicle pool and the initial rate of exocytosis. Neuron 14, 353-363.
28. WANG, X. H., ZHENG, J. Q. & POO, M. M. (1996). Effects of cytochalasin treatment on short-term synaptic plasticity at developing neuromuscular junctions in frogs. Journal of Physiology 491, 187-195.
29. WAYNE, N. L., KIM, J. & LEE, E. (1998). Prolonged hormone secretion from neuroendocrine cells of Aplysia is independent of extracellular calcium. Journal of Neuroendocrinology 10, 529-537.
30. 2+. Science 197, 67-69.
31. 2+ on stimulation-induced changes in transmitter release at the frog neuromuscular junction. Journal of General Physiology 76, 175-211.
32. 2+ at the frog neuromuscular junction. Journal of General Physiology 77, 503-529.
33. ZENISEK, D., STEYER, J. A. & ALMERS, W. (2000). Transport, capture and exocytosis of single synaptic vesicles at active zones. Nature 406, 849-854.