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Volumn 43, Issue 29, 2002, Pages 5061-5065

Regio- and stereocontrolled preparation of ±-substituted phosphonocrotonate derivatives

Author keywords

Alkylation; Macrocycle; Phosphonocrotonate; Polycyclisation; Stereocontrol

Indexed keywords

CROTONIC ACID DERIVATIVE; MANZAMINE A; PHOSPHONIC ACID DERIVATIVE;

EID: 0037100025     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)01001-8     Document Type: Article
Times cited : (15)

References (25)
  • 15
    • 84991418962 scopus 로고    scopus 로고
    • 2O revealed that rapid decomposition of the phosphonocrotonate anion occurred, leading to poor yields of recovered starting material
  • 16
    • 84991412765 scopus 로고    scopus 로고
    • The absence of γ-adducts probably reflects the greater steric hindrance of the phosphonate substituent as compared with the far less bulky and planar ester group
  • 17
    • 84991428056 scopus 로고    scopus 로고
    • note
  • 18
    • 84991428172 scopus 로고    scopus 로고
    • This is due to a slower decomposition of the lithium anion of phosphonate 11, thereby producing a higher overall yield. Since the separation of the mono- and dialkylated adducts is trivial, it is often advantageous to aim for complete conversions with good selectivity rather than excellent selectivity with moderate yields
  • 25
    • 84991428174 scopus 로고    scopus 로고
    • note


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.