Studies toward practical synthesis of (20S)-camptothecin family through catalytic enantioselective cyanosilylation of ketones: Improved catalyst efficiency by ligand-tuning

Tetrahedron Letters

Volumn 43, Issue 16, 2002, Pages 2923-2926

  Yabu, Kazuo ^a   Masumoto, Shuji ^a   Kanai, Motomu ^a,b   Curran, Dennis P ^c   Shibasaki, Masakatsu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Camptothecin; Catalyst loading; Catalytic enantioselective reaction; Chiral ligand; Cyanosilylation; Ketones; Ligand tuning

Indexed keywords

CAMPTOTHECIN; KETONE DERIVATIVE; LIGAND;

ARTICLE; CATALYSIS; CATALYST; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; CYANOSILATION; DRUG RESEARCH; DRUG SYNTHESIS; ENANTIOSELECTIVITY;

EID: 0037090145     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)00451-3     Document Type: Article

References (17)