Effects of membrane partitioning and other physical chemical properties on the apparent potency of "Membrane Active" compounds evaluated using red blood cell lysis assays

Analytical Biochemistry

Volumn 303, Issue 2, 2002, Pages 153-166

  Chapman, Darryl ^a   Buxser, Stephen ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CELLS; SODIUM CHLORIDE;

ALTERING PROPERTIES; CELL CONCENTRATIONS; EXPERIMENTAL PROTOCOLS; HUMAN RED BLOOD CELL; MEMBRANE DESTABILIZATION; MEMBRANE INTEGRITY; NACL CONCENTRATION; PHYSICAL CHEMICAL PROPERTY;

MEMBRANES;

AMPHOLYTE; AMPHOTERICIN B; DETERGENT; MEMBRANE LIPID; SODIUM CHLORIDE;

ADULT; ANALYTIC METHOD; ARTICLE; BACTERIAL GROWTH; CELL ASSAY; CELL MEMBRANE; DOSE RESPONSE; DRUG MECHANISM; DRUG POTENCY; ERYTHROCYTE; GROWTH INHIBITION; HEMOLYSIS; HUMAN; MALE; MEMBRANE DAMAGE; MEMBRANE STABILIZATION; NORMAL HUMAN; OSMOTIC STRESS; PRIORITY JOURNAL;

BACTERIA (MICROORGANISMS);

EID: 0037089485     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.2002.5588     Document Type: Article

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