Antibody directed against GD2 produces mechanical allodynia, but not thermal hyperalgesia when administered systemically or intrathecally despite its dependence on capsaicin sensitive afferents

Brain Research

Volumn 930, Issue 1-2, 2002, Pages 67-74

  Sorkin, L S ^a   Yu, A L ^a   Junger, H ^a   Doom, C M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

C fiber; Immunotherapy; Neuroimmune response; Pain

Indexed keywords

ANTIGEN; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; GANGLIOSIDE ANTIBODY; MYELIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY REACTION; ARTICLE; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; HYPERALGESIA; MALE; NONHUMAN; PERIPHERAL NERVE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; RAT; SENSORY NERVE; SPINAL CORD DORSAL HORN;

ANIMALS; ANTIBODIES, BLOCKING; ANTIBODIES, MONOCLONAL; BEHAVIOR, ANIMAL; CAPSAICIN; GANGLIOSIDES; HYPERALGESIA; INFUSIONS, INTRAVENOUS; INJECTIONS, SPINAL; MALE; NEURONS, AFFERENT; NOCICEPTORS; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0037087094     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)03408-4     Document Type: Article

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