Brucella abortus vaccine strain RB51 produces low levels of M-like O-antigen

Vaccine

Volumn 20, Issue 13-14, 2002, Pages 1820-1822

  Cloeckaert, Axel ^a   Zygmunt, Michel S ^a   Guilloteau, Laurence A ^a  

^a CEMAGREF   (France)

Author keywords

Brucella abortus; O chain; RB51; Vaccine

Indexed keywords

BACTERIAL POLYSACCHARIDE; BRUCELLA VACCINE; MONOCLONAL ANTIBODY; RB51;

ANTIBODY SPECIFICITY; ARTICLE; BACTERIAL STRAIN; BRUCELLA ABORTUS; BRUCELLOSIS; CATTLE; CATTLE DISEASE; CONTROLLED STUDY; INFECTION PREVENTION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, MONOCLONAL; BRUCELLA ABORTUS; BRUCELLA VACCINE; BRUCELLOSIS, BOVINE; CATTLE; FEMALE; GENES, BACTERIAL; O ANTIGENS; PREGNANCY;

EID: 0037086710     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(02)00035-X     Document Type: Article

References (12)

1. Biological properties of RB51; a stable rough strain of Brucella abortus
2. Serologic responses in diagnostic tests for brucellosis in cattle vaccinated with Brucella abortus 19 or RB51
3. Antibody responses to Brucella abortus 2308 in cattle vaccinated with B. abortus RB51
4. Serologic responses of Brucella abortus strain 19 calfhood-vaccinated cattle following adult vaccination with strain RB51
5. O-polysaccharide epitopic heterogeneity at the surface of Brucella spp. studied by enzyme-linked immunosorbent assay and flow cytometry
6. O-chain expression in the rough Brucella melitensis strain B115: Induction of O-polysaccharide-specific monoclonal antibodies and intracellular localization demonstrated by immunoelectron microscopy
7. DNA polymorphism at the Omp-31 locus of Brucella spp.: Evidence for a large deletion in Brucella abortus, and other species-specific markers
8. Transposon-derived Brucella abortus rough mutants are attenuated and exhibit reduced intracellular survival
9. Genetic organisation of the lipopolysaccharide O-antigen biosynthesis region of Brucella melitensis 16M (wbk)
10. Identification of the perosamine synthetase gene of Brucella melitensis 16M and involvement of lipopolysaccharide O-side chain in Brucella survival in mice and in macrophages
11. Complementation of Brucella abortus RB51 with a functional wboA gene results in O-antigen synthesis and enhanced vaccine efficacy but no change in rough phenotype and attenuation
12. Identification of an IS711 element interrupting the wboA gene of Brucella abortus vaccine strain RB51 and a PCR assay to distinguish strain RB51 from other Brucella species and strains