Deletions of the derivative chromosome 9 do not account for the poor prognosis associated with Philadelphia-positive acute lymphoblastic leukemia [4]

Blood

Volumn 99, Issue 6, 2002, Pages 2274-2275

  Reid, Alistair G ^a   Huntly, Brian J P ^a   Hennig, Eveline ^a   Niederwieser, Dietger ^a   Campbell, Lynda J ^a   Bown, Nick ^a   Telford, Nick ^a   Walker, Helen ^a   Grace, Colin D ^a   Deininger, Michael W ^a   Green, Anthony R ^a   Nacheva, Elisabeth P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; CHROMOSOME 9; CHROMOSOME DELETION; CHROMOSOME TRANSLOCATION; CHRONIC MYELOID LEUKEMIA; CLINICAL EXAMINATION; DISEASE COURSE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; LETTER; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL; PROGNOSIS; SEQUENCE ANALYSIS;

EID: 0037085762     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.6.2274     Document Type: Letter

References (15)

1. Acute lymphoblastic leukaemia
2. Clinical significance of cytogenetic abnormalities in adult acute lymphoblastic leukemia
3. The molecular biology of chronic myeloid leukemia
4. Chronic myeloid leukemia
5. Translocation of c-abl oncogene correlates with the presence of the Philadelphia chromosome in chronic myelocytic leukaemia
6. The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype
7. Frequent deletion of hSNF5/INI1, a component of the SWI/SNF complex, in chronic myeloid leukemia
8. Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia
9. Atypical BCR and ABL D-FISH patterns in chronic myeloid leukemia and their possible role in therapy
10. Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis
11. Deletions of the derivative chromosome 9 occur at the time of the Philadelphia translocation and provide a powerful and independent prognostic indicator in chronic myeloid leukaemia
12. Highly sensitive fluorescence in situ hybridization method to detect double BCR/ABL fusion and monitor response to therapy in chronic myeloid leukemia
13. The Philadelphia (Ph) chromosome in leukemia; II: Variant Ph translocations in acute lymphoblastic leukemia
14. The existence of lymphoid lineage restricted Philadelphia chromosome-positive acute lymphoblastic leukemia with heretogeneous bcr-abl rearrangement
15. The RAG protiens and V(D)J recombination: Complexes, ends and transposition