The solution structure of an oligonucleotide duplex containing a 2′-deoxyadenosine-3-(2-hydroxyethyl)-2′-deoxyuridine base pair determined by NMR and molecular dynamics studies

Nucleic Acids Research

Volumn 30, Issue 6, 2002, Pages 1371-1378

  Boulard, Yves ^a   Fazakerley, G Victor ^a   Sowers, Lawrence C ^b  

^a DIF   (France)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYURIDINE DERIVATIVE; HYDROGEN; HYDROXYL GROUP; OLIGONUCLEOTIDE; PROTON;

ARTICLE; CALCULATION; CHEMICAL INTERACTION; CONTROLLED STUDY; DNA REPAIR; DNA STRUCTURE; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SPECTROMETER; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

EID: 0037085740     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/30.6.1371     Document Type: Article

References (27)

1. Review of the mutagenicity of ethylene oxide
2. Genetic toxicity of some important epoxides
3. Epidemiologic support for ethylene oxide as a cancer-causing agent
4. Exposure-response analysis of cancer mortality in a cohort of workers exposed to ethylene oxide
5. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans. Allyls Compounds, Aldehydes, Epoxides and Peroxides
6. The mutagenic potential of ethylene oxide using the dominant-lethal assay in rats
7. Gene elimination in carcinogenesis: Reinterpretation of the somatic mutation theory
8. Heritable translocation and dominant-lethal mutation induction with ethylene oxide in mice
9. Lack of additive effect in mutagenesis of E. coli by UV-light and ethylene oxide
10. The mutagenicity of chloroethylene oxide, chloroacetaldehyde, 2-chloroethanol and chloroacetic acid, conceivable metabolites of vinyl chloride
11. Biological and chemical monitoring of occupational exposure to ethylene oxide
12. Persistently elevated sister chromatid exchanges in ethylene oxide-exposed primates: The role of a subpopulation of high frequency cells
13. Genotoxic effects of ethylene oxide and propylene oxide in mouse bone marrow cells
14. In vitro reaction of ethylene oxide with DNA and characterization of DNA adducts
15. The role of 3-hydroxyethyldeoxyuridine in mutagenesis by ethylene oxide
16. Solution structure of two mismatches G.G and I.I in the K-ras gene context by nuclear magnetic resonance and molecular dynamics
17. Solution structure as a function of pH of two central mismatches, C·T and C·C, in the 29 to 39 K-ras gene sequence, by nuclear magnetic resonance and molecular dynamics
18. Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy
19. Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions
20. An abasic site in DNA. Solution conformation determined by proton NMR and molecular mechanics calculations
21. A second generation force field for the simulation of proteins, nucleic acids and organic molecules
22. Conformations of nicked and gapped DNA structures by NMR and molecular dynamic simulations in water
23. Binding of Net-Fla, a netropsin-flavin hydrid molecule, to DNA: Molecular mechanics and dynamics studies in vacuo and in water solution
24. Object Command Language: A formalism to build molecular models and to analyze structural parameters in macromolecules, with applications to nucleic acids
25. MORCAD, an object oriented molecular modelling package running on IBM/RS6000 and SGI 4Dxxx workstations
26. MOLMOL: A program for display and analysis of macromolecular structures