Comparative analysis of hairpin ribozyme structures and interference data

Nucleic Acids Research

Volumn 30, Issue 6, 2002, Pages 1287-1291

  Ryder, Sean P ^a,b   Strobel, Scott A ^a  

^a YALE UNIVERSITY   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATE; RIBOZYME; RNA;

CATALYSIS; CHEMICAL ANALYSIS; CLUSTER ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DATA ANALYSIS; GENE CLUSTER; GENE REARRANGEMENT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACID ANALYSIS; PRIORITY JOURNAL; PUBLICATION; REVIEW; RNA CONFORMATION; RNA STRUCTURE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

RUMEX;

EID: 0037085738     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/30.6.1287     Document Type: Review

References (25)

1. Ribozyme chemogenetics
2. Synthetic oligoribonucleotides carrying site-specific modifications for RNA structure-function analysis
3. Complementary sets of noncanonical base pairs mediate RNA helix packing in the group I intron active site
4. A minor groove RNA triple helix within the catalytic core of a group I intron
5. Nucleotide sequence and newly formed phosphodiester bond of spontaneously ligated satellite tobacco ringspot virus RNA
6. Sequences required for self-catalysed cleavage of the satellite RNA of tobacco ringspot virus
7. RNA catalytic properties of the minimum (-)sTRSV sequence
8. Binding and cleavage of nucleic acids by the 'hairpin' ribozyme
9. Ribozyme structures and mechanisms
10. Solution structure of the loop B domain from the hairpin ribozyme
11. Solution structure of loop A from the hairpin ribozyme from tobacco ringspot virus satellite
12. Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysis
13. Nucleotide analog interference mapping of the hairpin ribozyme: Implications for secondary and tertiary structure formation
14. Structural basis for the guanosine requirement of the hairpin ribozyme
15. Novel guanosine requirement for catalysis by the hairpin ribozyme
16. Purine functional groups in essential residues of the hairpin ribozyme required for catalytic cleavage of RNA
17. Investigation of adenosine base ionization in the hairpin ribozyme by nucleotide analog interference mapping
18. Essential nucleotide sequences and secondary structure elements of the hairpin ribozyme
19. Inter-domain cross-linking and molecular modelling of the hairpin ribozyme
20. Structure-mapping of the hairpin ribozyme. Magnesium-dependent folding and evidence for tertiary interactions within the ribozyme-substrate complex
21. A conformational change in the 'loop E-like' motif of the hairpin ribozyme is coincidental with domain docking and is essential for catalysis
22. Four ribose 2′-hydroxyl groups essential for catalytic function of the hairpin ribozyme
23. Base and sugar requirements for RNA cleavage of essential nucleoside residues in internal loop B of the hairpin ribozyme: Implications for secondary structure
24. The role of essential pyrimidines in the hairpin ribozyme-catalysed reaction
25. Real-time monitoring of hairpin ribozyme kinetics through base-specific quenching of fluorescein-labeled substrates