BSE and variant CJD: About the difficulties to establish a new pathogenetic principle;BSE und variante CJK: Von den schwierigkeiten, ein neues krankheitsprinzip zu etablieren

Deutsche Medizinische Wochenschrift

Volumn 127, Issue 7, 2002, Pages 344-346

  Schulz Schaeffer, Walter J ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

AMINO ACID SEQUENCE; BOVINE SPONGIFORM ENCEPHALOPATHY; CREUTZFELDT JAKOB DISEASE; DEGENERATIVE DISEASE; DISINFECTION; GENETIC ANALYSIS; PRION DISEASE; SHORT SURVEY;

ANIMALS; CATTLE; CREUTZFELDT-JAKOB SYNDROME; CRICETINAE; ENCEPHALOPATHY, BOVINE SPONGIFORM; HUMANS; MACACA; MICE; MICE, KNOCKOUT; MUTATION; PAN TROGLODYTES; PRIONS; RISK FACTORS; SCRAPIE; TIME FACTORS;

EID: 0037083504     PISSN: 00120472     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-20152     Document Type: Short Survey

References (31)

1. Genetic and infectious prion diseases
2. Friendly fire in medicine. Hormones, homografts, and Creutzfeldt-Jakob disease
3. Experimental transmission of a kuru-like syndrome to chimpanzees
4. Inherited prion diseases and transmission to rodents
5. Identification of a protein that purifies with the scrapie prion
6. Chemical disinfection of Creutzfeldt-Jakob disease virus
7. Resistance of scrapie infectivity to steam autoclaving after formaldehyde fixation and limited survival after ashing at 360°C: Practical and theoretical implications
8. Unusual resistance to ionizing radiation of the viruses of kuru, Creutzfeldt-Jakob disease, and scrapie
9. Properties of the transmissible agent derived from chronic spongiform encephalopathy
10. The search for scrapie agent nucleic acid
11. The scrapie enigma - Insights from radiation experiments
12. The nature of the scrapie agent: The virus theory
13. Conversion of α-helices into β-sheets features in the formation of the scrapie prion proteins
14. A »unified theory« of prion propagation
15. Novel proteinaceous infectious particles cause scrapie
16. Mice devoid of PrP are resistant to scrapie
17. Molecular genetics of human prion diseases in Germany
18. Experiments with scrapie with special reference to the nature of the agent and the pathology of the disease
19. Precautions in medical care of, and in handling materials from, patients with transmissible virus dementia (Creutzfeldt-Jakob disease)
20. Pathogenesis of mouse scrapie: Dynamics of agent replication in spleen, spinal cord and brain after infection by different routes
21. Molecular properties, partial purification and assay by incubation period measurements of the hamster scrapie agent
22. Early accumulation of pathological PrP in the enteric nervous system and gut-associated lymphoid tissue of hamsters orally infected with scrapie
23. Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves
24. Pathogenesis of natural scrapie in sheep
25. Detection of PrP(Sc) in subclinical BSE with the paraffin-embedded tissue (PET) blot
26. BSE transmission to macaques
27. Transmissions to mice indicate that »new variant« CJD is caused by the BSE agent
28. Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans
29. Sequential appearance and accumulation of pathognomonic markers in the central nervous system of hamsters orally infected with scrapie
30. A study of the inheritance of susceptibility to bovine spongiform encephalopathy
31. Incidence of variant Creutzfeldt-Jakob disease in the UK