Clinical link between p53 and angiogenesis in lung cancer

Journal of Clinical Oncology

Volumn 20, Issue 4, 2002, Pages 883-884

  Freemantle, Sarah J ^a   Dmitrovsky, Ethan ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ANGIOGENESIS; CANCER GROWTH; CELL PROLIFERATION; DISEASE ASSOCIATION; EDITORIAL; ENDOTHELIUM CELL; IMMUNOHISTOCHEMISTRY; LUNG CARCINOMA; METASTASIS; MICROVASCULATURE; PRIORITY JOURNAL; TUMOR VASCULARIZATION;

EID: 0037083427     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2002.20.4.883     Document Type: Editorial

References (19)

1. P53 mutations in cancers
2. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
3. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
4. Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression
5. Wild-type p53 and v-src exert opposing influences on human vascular endothelial growth factor gene expression
6. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1 alpha
7. Aberrant p53 expression correlates with expression of vascular endothelial growth factor mRNA and interleukin-8 mRNA and neoangiogenesis in non-small-cell lung cancer
8. P53 immunostaining positivity is associated with reduced survival and is imperfectly correlated with gene mutations in resected non-small cell lung cancer: A preliminary report of LCSG 871
9. Aberrant expression of p53 or the epidermal growth factor receptor is frequent in early bronchial neoplasia, and coexpression precedes squamous cell carcinoma development
10. Regulation of p53 downstream genes
11. A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis
12. Clinical applications of angiogenic growth factors and their inhibitors
13. Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma
14. Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
15. Prognostic value of vascular endothelial growth factor in breast cancer
16. Coexpression of proangiogenic factors IL-8 and VEGF by human head and neck squamous cell carcinoma involves coactivation by MEK-MAPK and IKK-NF-kappa B signal pathways
17. Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression
18. Inhibition of growth factor production and angiogenesis in human cancer cells by ZD1839 (Iressa), a selective epidermal growth factor receptor tyrosine kinase inhibitor
19. Tyrosine kinase inhibitors-ZD1839 (Iressa)