Inhibitory effects of apoptotic cell ingestion upon endotoxin-driven myeloid dendritic cell maturation

Journal of Immunology

Volumn 168, Issue 4, 2002, Pages 1627-1635

  Stuart, Lynda M ^a   Lucas, Mark ^a   Simpson, Cathy ^a   Lamb, Jonathan ^a   Savill, John ^a   Lacy Hulbert, Adam ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD86 ANTIGEN; ENDOTOXIN; INTERLEUKIN 10; INTERLEUKIN 12; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CELL FATE; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; MOUSE; NONHUMAN; NORMAL HUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; REGULATORY MECHANISM; T LYMPHOCYTE ACTIVATION; TUMOR IMMUNITY;

EID: 0037083280     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.4.1627     Document Type: Article

References (35)

1. The induction of tolerance by dendritic cells that have captured apoptotic cells
2. Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures
3. Dendritic cells and the control of immunity
4. Natural adjuvants: Endogenous activators of dendritic cells
5. Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
6. Processing of engulfed apoptotic bodies yields T cell epitopes
7. 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes
8. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
9. Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class 11 products of dendritic cells
10. Clearing the way to mechanisms of autoimmunity
11. Phagocytosis and clearance of apoptotic cells is mediated by MER
12. A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo
13. Dendritic cells in transplantation: Friend or foe?
14. 2, and PAF
15. 3)
16. A receptor for phosphafidylserine-specific clearance of apoptotic cells
17. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
18. Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis
19. Kinetics of dendritic cell activation: Impact on priming of TH1, TH2 and nonpolarized T cell
20. Interleukin-10 does not affect phagocytosis of particulate antigen by bone marrow-derived dendritic cells but does impair antigen presentation
21. Regulatory activity of autocrine IL-10 on dendritic cell functions
22. Immunosuppressive effects of apoptotic cells
23. TGF-β released by apoptotic T cells contributes to an immunosuppressive milieu
24. Corpse clearance defines the meaning of cell death
25. Phagocytosis of apoptotic neutrophils does not induce macrophage release of thromboxane B2
26. 5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells
27. Selective suppression of interleukin-12 induction after macrophage receptor ligation
28. The taming of IL-12: Suppressing the production of proinflammatory cytokines
29. Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells
30. A role for CD36 in the regulation of dendritic cell function
31. Immunogenicity of apoptotic cells in vivo: Role of antigen load, antigen-presenting cells, and cytokines
32. Intravenous injection of apoptotic leukocytes enhances bone marrow engraftment across major histocompatibility barriers
33. Dendritic cell heterogeneity in vivo: Two functionally different dendritic cell populations in rat intestinal lymph can be distinguished by CD4 expression
34. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity
35. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes