Overexpression of ornithine decarboxylase enhances endothelial proliferation by suppressing endostatin expression

Blood

Volumn 99, Issue 4, 2002, Pages 1478-1481

  Nemoto, Takahiro ^a,b,c,d   Hori, Hisae ^a,b,c,d   Yoshimoto, Masataka ^a,b,c,d   Seyama, Yousuke ^a,b,c,d   Kubota, Shunichiro ^a,b,c,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d CANCER INSTITUTE HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 8; ENDOSTATIN; ORNITHINE DECARBOXYLASE;

ANGIOGENESIS; ARTICLE; BREAST CANCER; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH;

EID: 0037082490     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.4.1478     Document Type: Article

References (17)

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15. Alpha-difluoromethylornithine induces apoptosis as well as antiangiogenesis in the inhibition of tumor growth and metastasis in a human gastric cancer model
16. Tumor angiogenesis and polyamines: Alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits B16 melanoma-induced angiogenesis in vivo and the proliferation of vascular endothelial cells in vitro
17. Enhanced tumor growth of both primary and established human and murine tumor cells in athymic mice after coinjection with Matrigel