A functional platelet fibrinogen receptor with a deletion in the cysteine-rich repeat region of the β3 integrin: The Oea alloantigen in neonatal alloimmune thrombocytopenia

Blood

Volumn 99, Issue 4, 2002, Pages 1205-1214

  Santoso, Sentot ^a,b,c   Kiefel, Volker ^a,b   Richter, Ina G ^a,b   Sachs, Ulrich J H ^a,b   Rahman, Abdul ^a,b   Carl, Bettina ^a,b   Kroll, Harmut ^a,b  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c UNIVERSITY HOSPITAL GIESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; COMPLEMENTARY DNA; CYSTEINE; FIBRINOGEN; FIBRINOGEN RECEPTOR; GLYCOPROTEIN IIIA; INTEGRIN; LYSINE; PROLINE; THROMBOCYTE RECEPTOR;

ADULT; ALLELE; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CASE REPORT; CONFORMATIONAL TRANSITION; DISULFIDE BOND; FEMALE; GENE DELETION; HUMAN; HUMAN CELL; MALE; MOLECULAR WEIGHT; MUTATION; NEWBORN; NEWBORN ALLOIMMUNE THROMBOCYTOPENIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; SEQUENCE ANALYSIS; THROMBOCYTOPENIA;

EID: 0037082482     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V99.4.1205     Document Type: Article

References (36)

1. Integrins: Versatility, modulation, and signaling in cell adhesion
2. 3 and platelet function
3. 3: Inside-out, outside-in, and sideways
4. Platelet integrin GPIIb/IIIa: Structure-function correlations: An update lessons from other integrins
5. The molecular genetic basis of Glanzmann thrombasthenia in the Iraqi-Jewish and Arab populations in Israel
6. A redox site involved in integrin activation
7. Hematologically important mutations: Glanzmann thrombasthenia
8. Human platelet-specific alloantigens: Update
9. 3 to segments that encode alloartigenic sites and functional domains of β3 in human beings
10. The alloimmune thrombocytopenic syndromes
11. Clinical aspects and typing of platelet alloantigens
12. Platelet glycoprotein polymorphism as risk factors for thrombosis
13. Platelet polymorphisms in thrombotic disorders
14. A2 polymorphism of integrin β3 enhances outside-in signaling and adhesive functions
15. A2 alloantigen on the function of β3 integrins in platelets
16. Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): A new tool for the identification of platelet reactive antibodies
17. 2)
18. Monoclonal antibodies against antigens of the human platelet surface: Preparation and properties
19. Quantitation of glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP3
20. A conformation dependent epitope of GPIIIa
21. a and affects collagen collagen-induced aggregation
22. Protein sequence of endothelial glycoprotein IIIa derived from cDNA clone: Identity with platelet glycoprotein IIIa and similarity to "integrin"
23. The genomic organization of platelet glycoprotein IIIa
24. A typing by allele-specific restriction analysis
25. Blymphoblastoid cell lines as source for reference DNA for human platelet and neutrophil antigen genotyping
26. b platelet alloantigenic epitopes
27. Integrin-mediated activation of focal adhesion formation or integrin activation: Studies with activated and inhibitor β3 cytoplasmic mutants
28. Evidence that platelet glyco-protein IIIa has a large disulfide-bonded loop that is susceptible to proteolytic cleavage
29. Proteolytic dissection of the isolated platelet membrane fibrinogen receptor, integrin GPIIb/IIIa: Localization of GPIIb and GPIIIa sequences putatively involved in the subunit interface an in intrasubunit and intrachain contacts
30. Assignment of disulfide bonds in human platelet glycoprotein IIIa: A disulphide pattern for the β-subunits of the integrin family
31. a alfoantigen system of GPIIIa
32. A comparative analysis of cDNA-derived sequences for rat and mouse β3 integrins (GPIIIa) with their human counterpart
33. The integrin αIIbβ3, platelet glycoprotein IIb-IIIa can form a functionally active heterodimer complex without the cysteine-rich repeats of the β3 subunits
34. 3
35. Human platelet alloantigens: Recent findings, new perspectives
36. Integrin expression in early amphibian embryos: cDNA cloning and characterization of Xenopus β1, β2, β3, and β6 subunits