Velocity of actomyosin sliding in Vitro is reduced in dystrophic mouse diaphragm

American Journal of Respiratory and Critical Care Medicine

Volumn 165, Issue 2, 2002, Pages 250-253

  Coirault, Catherine ^a,b   Lambert, Francine ^a,b   Pourny, Jean Claude ^a,b   Lecarpentier, Yves ^a,b  

^a LABORATOIRE D OPTIQUE APPLIQUÉE   (France)

^b BICÊTRE HOSPITAL   (France)

Author keywords

Crossbridge; In vitro motility assays; Mdx mice; Myosin

Indexed keywords

ACTIN; DYSTROPHIN; MYOSIN; MYOSIN ADENOSINE TRIPHOSPHATASE;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIAPHRAGM MUSCLE; IN VITRO STUDY; MALE; MOUSE; MUSCULAR DYSTROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; SEMITENDINOUS MUSCLE;

EID: 0037080574     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.165.2.2105088     Document Type: Article

References (39)

1. Conservation of the Duchenne muscular dystrophy gene in mice and humans
2. The Duchenne muscular dystrophy gene product is localized in sarcolemma of human skeletal muscle
3. The mdx mouse and mdx diaphragm. Implications for the pathogenesis of Duchenne muscular dystrophy
4. Dystrophin protects the sarcolemma from stresses developed during muscle contraction
5. Calcium entry through stretch-inactivated ion channel in mdx myotubes
6. Protcolysis results in altered leak channel kinetics and elevated free calcium in mdx muscle
7. Increased activity of calcium leak channels in myotubes of Duchenne human and mdx mouse origin
8. Muscular dystrophy and activation of proteinases
9. Calpains are activated in necrotic fibers from mdx dystrophic mice
10. Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice
11. How does dystrophin deficiency lead to muscle degeneration? Evidence from the mdx mouse
12. The sarcoplasmic reticulum calcium pump is functionally altered in dystrophic muscle
13. Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice
14. Myosin molecular motor dysfunction in dystrophic mouse diaphragm
15. Muscle structure and theories of contraction
16. Mechanics, energetics, and crossbridge kinetics of rabbit diaphragm during congestive heart failure
17. The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy
18. Fluorescent actin filaments move on myosin fixed to a glass surface
19. Differential expression of muscular dystrophy in diaphragm versus hindlimb muscles of mdx mice
20. Purification of muscle actin
21. Myosin-specific adaptations of the motility assay
22. The stiffness of rabbit skeletal actomyosin cross-bridges determined with an optical tweezers transducer
23. Electrophoretic analysis of contractile proteins of the diaphragm in chronically hypoxic rats
24. Analysis of skeletal and cardiac muscle from knock-out and normal mice by high resolution separation of myosin heavy-chain isoforms
25. The in vitro motility assay: A window into the myosin molecular motor
26. Sarcomeric myosin isoforms: Fine tuning of a molecular motor
27. In vitro actin filament sliding velocities produced by mixtures of different types of myosin
28. In vitro motility speed from slow myosin extracted from single soleus fibres from young and old rats
29. Neither changes in phosphorus metabolite levels nor myosin isoforms can explain the weakness in age mouse muscle
30. Electron paramagnetic resonance reveals age-related myosin structural changes in rat skeletal muscle fibers
31. Adaptations in myosin heavy chain expression and contractile function in dystrophic mouse diaphragm
32. Maximum velocity of shortening in relation to myosin isoform composition in single fibres from human skeletal muscles
33. Force-velocity relationship and myosin heavy chain isoform compositions of skinned fibres from rat skeletal muscle
34. Stretch activation, unloaded shortening velocity, and myosin heavy chain isoforms of rat skeletal muscle fibres
35. Unloaded shortening velocity myosin heavy chain and alkali light chain isoform composition in rat skeletal muscle fibres
36. Actomyosin interactions in a novel single muscle fiber in vitro motility assay
37. How molecular motors work
38. Kinetics tuning of myosin via a flexible loop adjacent to the nucleotide binding pocket
39. Severe mechanical dysfunction in pharyngeal muscle from adult mdx mice