A 6-exo-trig radical cyclization approach to the hydrochrysene skeleton

Tetrahedron Letters

Volumn 43, Issue 42, 2002, Pages 7605-7608

  Zhang, Xuqing ^a,b   Guzi, Timothy ^a   Pettus, Liping ^a   Schultz, Arthur G ^a  

^a Rensselaer Polytechnic Institute   (United States)

^b JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHRYSENE DERIVATIVE; HYDROCHRYSENE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL PARAMETERS; CHEMICAL STRUCTURE; CYCLIZATION; REDUCTION; SYNTHESIS;

EID: 0037078399     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)01728-8     Document Type: Article

References (26)

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16. Synthesis of the alkylating agents:
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21. 3) 196.8, 172.6, 151.0, 148.3, 144.4, 133.7, 131.4, 127.6, 127.5, 127.0, 126.1, 124.9, 121.1, 118.0, 77.7, 62.1, 60.3, 53.1, 51.8, 47.6, 14.1, 13.0.
22. 3B, see: (a) Nozaki, K.; Oshima, K.; Utimoto, K. J. Am. Chem. Soc. 1987, 109, 2547; (b) Satoh, S.; Sodeoka, M.; Sasai, H.; Shibasaki, M. J. Org. Chem. 1991, 56, 2278; (c) Brown, H. C.; Midland, M. M. Angew. Chem., Int. Ed. Engl. 1972, 11, 692.
23. 3B, see: (a) Nozaki, K.; Oshima, K.; Utimoto, K. J. Am. Chem. Soc. 1987, 109, 2547; (b) Satoh, S.; Sodeoka, M.; Sasai, H.; Shibasaki, M. J. Org. Chem. 1991, 56, 2278; (c) Brown, H. C.; Midland, M. M. Angew. Chem., Int. Ed. Engl. 1972, 11, 692.
24. 3B, see: (a) Nozaki, K.; Oshima, K.; Utimoto, K. J. Am. Chem. Soc. 1987, 109, 2547; (b) Satoh, S.; Sodeoka, M.; Sasai, H.; Shibasaki, M. J. Org. Chem. 1991, 56, 2278; (c) Brown, H. C.; Midland, M. M. Angew. Chem., Int. Ed. Engl. 1972, 11, 692.
25. ++1, 100).
26. 2: C, 82.86; H, 6.62. Found: C, 82.75; H, 6.68%.