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Journal of the American Chemical Society

Volumn 124, Issue 32, 2002, Pages 9476-9488

Total synthesis of deamido bleomycin A2, the major catabolite of the antitumor agent bleomycin

(5) Zou, Ying a Fahmi, Nour Eddine a Vialas, Corine a Miller, Guy M a Hecht, Sidney M a

a UNIVERSITY OF VIRGINIA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITUMOR ACTIVITIES;

ANTIBIOTICS; BIOASSAY; DNA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

SYNTHESIS (CHEMICAL);

BLEOMYCIN A2; BLEOMYCIN DERIVATIVE; BLEOMYCIN HYDROLASE; DEAMIDOBLEOMYCIN A2; DEAMIDONORBLEOMYCIN A2; N ALPHA BUTYLOXYCARBONYL N BETA [1 AMINO 3 (4 AMINO 6 CARBONYL 5 METHYLPYRIMIDIN 2 YL)PROPION 3 YL] BETA AMINOALANINE TERT BUTYL ESTER; PLASMID DNA; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DNA CLEAVAGE; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS;

ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; HUMANS; HYDROLASES;

EID: 0037077629 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja012741l Document Type: Article

Times cited : (42)

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