Effects of local repositioning of charged surface residues on the kinetics of protein dimerization probed by Brownian dynamics simulations

Journal of Molecular Structure: THEOCHEM

Volumn 592, Issue 1-3, 2002, Pages 37-45

  Fisher, Eric W ^a   Rojnuckarin, Atipat ^b   Kim, Sangtae ^c  

^a UNIVERSITY OF ILLINOIS AT SPRINGFIELD   (United States)

^b ARQULE INC   (United States)

^c ELI LILLY AND COMPANY   (United States)

Author keywords

Computer simulation; Electrostatic steering; Hemoglobin; Protein association kinetics; Weighted ensemble Brownian dynamics

Indexed keywords

AMINO ACID; ARGININE; GLYCINE; HEME; PROPIONIC ACID;

BINDING KINETICS; BIOTRANSFORMATION; CONFERENCE PAPER; CORRELATION ANALYSIS; DIMERIZATION; GENE DELETION; GENE MUTATION; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; OBSERVATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN INTERACTION; SIMULATION; SURFACE CHARGE; SURFACE PROPERTY;

EID: 0037072718     PISSN: 01661280     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-1280(02)00224-5     Document Type: Conference Paper

References (27)