The putative effector-binding site of Leishmania mexicana pyruvate kinase studied by site-directed mutagenesis

FEBS Letters

Volumn 514, Issue 2-3, 2002, Pages 255-259

  Hannaert, Véronique ^a   Yernaux, Cédric ^a   Rigden, Daniel J ^b   Fothergill Gilmore, Linda A ^c   Opperdoes, Fred R ^a   Michels, Paul A M ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA   (Brazil)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Allostery; Fructose 2,6 bisphosphate; Glycolysis; Leishmania mexicana; Pyruvate kinase

Indexed keywords

FRUCTOSE 2,6 BISPHOSPHATE; PYRUVATE KINASE;

ALLOSTERISM; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME KINETICS; ENZYME PURIFICATION; LEISHMANIA MEXICANA; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS;

ALLOSTERIC REGULATION; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; ENZYME ACTIVATION; ESCHERICHIA COLI; FRUCTOSEDIPHOSPHATES; KINETICS; LEISHMANIA MEXICANA; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTOZOAN PROTEINS; PYRUVATE KINASE; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

EUKARYOTA; LEISHMANIA MEXICANA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037070554     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(02)02374-8     Document Type: Article

References (22)