A single point mutation in ecdysone receptor leads to increased ligand specificity: Implications for gene switch applications

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 23, 2002, Pages 14710-14715

  Kumar, M B ^a   Fujimoto, T ^a   Potter, D W ^a   Deng, Q ^a   Palli, S R ^b  

^a RheoGene LLC   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; ECDYSONE; ECDYSONE RECEPTOR; ECDYSTEROID; HORMONE RECEPTOR; LIGAND; NONSTEROID ANTIINFLAMMATORY AGENT; STEROID; UNCLASSIFIED DRUG;

ARTICLE; DEVELOPMENT; GENE CONTROL; GENE SWITCHING; GENE THERAPY; GENETIC TRANSCRIPTION; GENOMICS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RECEPTOR BINDING; REPRODUCTION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; GRASSHOPPERS; LIGANDS; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; RECEPTORS, STEROID; SUBSTRATE SPECIFICITY;

CHORISTONEURA FUMIFERANA; HEXAPODA; INSECTA; MAMMALIA;

EID: 0037069431     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.222278999     Document Type: Article

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