Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 1

Journal of Medicinal Chemistry

Volumn 45, Issue 19, 2002, Pages 4282-4299

  Kühler, Thomas C ^a   Swanson, Marianne ^a   Christenson, Beritte ^a   Klintenberg, Ann Charlotte ^a,b   Lamm, Bo ^a   Fägerhag, Jonas ^a   Gatti, Roberto ^a,c   Ölwegård Halvarsson, Maria ^a   Shcherbuchin, Vladimir ^a   Elebring, Thomas ^a   Sjöström, Jan Erik ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b Hassle Lakemedel AB   (Sweden)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[(2 PYRIDYL)METHYL]THIO] 1H BENZIMIDAZOLE; 2 [[[2 METHYL 3 [(2 MORPHOLINO)ETHYLTHIO]PHENYL]METHYL]THIO] 1H BENZIMIDAZOLE; 2 [[[2 METHYL 3 [2 (1,2,4 TRIAZOL 1 YL)ETHYLTHIO]PHENYL]METHYL]THIO] 1 H BENZIMIDAZOLE; 2 [[[2 METHYL 3 [2 (2 METHYL 5 NITROIMIDAZOL 1 YL)ETHYLTHIO]PHENYL]METHYL]THIO] 1 H BENZIMIDAZOLE; 2 [[[2 METHYL 3 [2 [2 (2 METHOXYETHOXY)ETHOXY]ETHYLTHIO]PHENYL]METHYL]THIO] 1H BENZIMIDAZOLE; 2 [[[2 METHYL 3 [2 [2 [2 [2 (2 METHOXYETHOXY)ETHOXY]ETHOXY]ETHOXY]ETHYLTHIO]PHENYL]METHYL]THIO] 1H BENZIMIDAZOLE; BENZIMIDAZOLE DERIVATIVE; CLARITHROMYCIN; OMEPRAZOLE; PROTON PUMP INHIBITOR; SULFIDE; UNCLASSIFIED DRUG;

ARTICLE; BACTERICIDAL ACTIVITY; DRUG OXIDATION; DRUG STRUCTURE; HELICOBACTER PYLORI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

EID: 0037068650     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0208673     Document Type: Article

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