Arsenite-induced reactive oxygen species and the repression of α-tocopherol in the MGC-803 cells

European Journal of Pharmacology

Volumn 448, Issue 1, 2002, Pages 11-18

  Chen, Ai ^a   Cao, En Hua ^a   Zhang, Tong Cun ^a   Qin, Jing Fen ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

Author keywords

tocopherol; Apoptosis; Arsenite; Ca2+, intracellular; MGC 803 cell; Reactive oxygen species

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; ALPHA TOCOPHEROL; ARSENIC TRIOXIDE; CALCIUM ION; CELL NUCLEUS DNA; DNA FRAGMENT; LIPID PEROXIDE; PHOSPHOLIPASE C INHIBITOR; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; ARSENOUS ACID DERIVATIVE; CALCIUM; DNA;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER CELL; CELL STRAIN; CONTROLLED STUDY; DNA STRAND BREAKAGE; DOSE RESPONSE; DRUG EFFECT; HUMAN; HUMAN CELL; LIPID PEROXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; CELL CULTURE; DRUG INTERACTION; METABOLISM;

ALPHA-TOCOPHEROL; APOPTOSIS; ARSENITES; CALCIUM; DNA; DRUG INTERACTIONS; HUMAN; LIPID PEROXIDATION; REACTIVE OXYGEN SPECIES; SUPEROXIDES; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED; HUMANS;

EID: 0037067355     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)01901-5     Document Type: Article

References (42)

1. Induction of heme oxygenase: A general response to oxidant stress in cultured mammalian cells
2. Stimulation of reactive oxygen, but not reactive nitrogen species, in vascular endothelial cells exposed to low levels of arsenite
3. Evidence for an endothelial cell NADH/NADPH oxidase using electron spin resonance spectroscopy
4. Oxidative stress as a mediator of apoptosis
5. Cross-resistance to heavy metals in hydrogen peroxide-resistant CHO cell variants
6. DNA damage induced by hypocrellin A photosensitization
7. Study of DNA damage induced by liposome peroxidation
8. Effect of natural antioxidant tanshinone II-A on oxidative DNA damage by lipid peroxidation in liver cells
9. Photodynamic action initiate apoptosis by activating the lipid single translation system
10. 3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RARα/PML protein
11. 2-purinergic receptors for extracellular ATP
12. DNA damage in arsenite- and cadmium-treated bovine aortic endothelial cells
13. P22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells
14. NAD(P)H oxidase. Role in cardiovascular biology and disease
15. Dithiothreitol enhances arsenic trioxide-induced apoptosis in NB4 cells
16. Metallothionein-II and ferritin H mRNA levels are increased in arsenite-exposed HeLa cells
17. Oxygen free radicals and iron in relation to biology and medicine, some problems and concepts
18. 2+ stores to inositol 1,4,5,-trisphosphate in human endothelial cells
19. Clinical study on the treatment of acute promyelocytic leukemia mainly with composite Indigo Naturalis tablets
20. Reactive oxygen species are downstream mediators of p53-dependent apoptosis
21. ·-
22. Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family
23. Modulation of cellular antioxidant defense activities by sodium arsenite in human fibroblasts
24. Detection of mitochondria-derived reactive oxygen species production by the chemilumigenic probes lucigenin and luminol
25. Induction of oxyradicals by arsenic, implication for mechanism of genotoxicity
26. Inhibition of vascular NADH/NADPH oxidase activity by thiol reagents, lack of correlation with cellular glutathione redox status
27. Is the genotoxic effect of arsenic mediated by oxygen free radicals
28. Stimulation of a vascular smooth muscle cell NAD(P)H oxidase by thrombin. Evidence that p47phox may participate in forming this oxidase in intro and in vivo
29. NADH oxidase activation is involved in arsenite-induced oxidative DNA damage in human vascular smooth muscle cells
30. Vascular oxidant stress early after balloon injury. Evidence for increased NAD(P)H oxidoreductase activity
31. Cell transformation by the superoxide-generating oxidase Mox 1
32. P53: Death star
33. Active oxygen species are involved in the induction of micronuclei by arsenite in XRS-5 cells
34. Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species
35. Glutathione peroxidase and catalase modulate the genotoxicity of arsenite
36. Mechanisms involved in sodium arsenite-induced apoptosis of human neutrophils
37. Arsenite induces p53 accumulation through an ATM-dependent pathway in human fibroblast
38. Rapid and specific reactive oxygen species generation via NADPH oxidase activation during Fas-mediated apoptosis
39. Induction of apoptosis and inhibition of human gastric cancer MGC-803 cell growth by arsenic troxide
40. 2+ and apoptosis using Fluo-3 and Hoechst 33342
41. Opposite biological effects of arsenic trioxide and arsacetin involve a different regulation of signaling in human gastric cancer MGC-803 cells