Full season efficacy of moxidectin microsphere sustained release formulation for the prevention of heartworm (Dirofilaria immitis) infection in dogs

Veterinary Parasitology

Volumn 110, Issue 1-2, 2002, Pages 85-91

  Genchi, Claudio ^a   Rossi, Luca ^b   Cardini, Giovanni ^c   Kramer, Laura H ^d   Venco, Luigi ^e   Casiraghi, Maurizio ^a   Genchi, Marco ^a   Agostini, Alessandro ^e  

^a UNIVERSITY OF MILAN   (Italy)

^b Universit degli Studi   (Italy)

^c UNIVERSITY OF PISA   (Italy)

^d UNIVERSITY OF PARMA   (Italy)

^e Viale Cremona   (Italy)

Author keywords

Dirofilaria immitis; Dog; Full season activity; Moxidectin microsphere SR injectable formulation

Indexed keywords

MOXIDECTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIROFILARIA IMMITIS; DISEASE TRANSMISSION; DOG; DRUG EFFICACY; DRUG SAFETY; ENDEMIC DISEASE; FEMALE; INJECTION SITE; MALE; MICROFILARIA; NONHUMAN; PAIN; PARASITOSIS; PROPHYLAXIS; SUSTAINED RELEASE PREPARATION;

ADMINISTRATION, ORAL; ANIMALS; ANTHELMINTICS; ANTI-BACTERIAL AGENTS; ANTIGENS, HELMINTH; DELAYED-ACTION PREPARATIONS; DIROFILARIA IMMITIS; DIROFILARIASIS; DOG DISEASES; DOGS; ENDEMIC DISEASES; FEMALE; INJECTIONS, SUBCUTANEOUS; ITALY; MACROLIDES; MALE; MICROFILARIA; MICROSPHERES;

CANIS FAMILIARIS; DIROFILARIA IMMITIS;

EID: 0037065236     PISSN: 03044017     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4017(02)00325-4     Document Type: Article

References (12)

1. Blagburn, B.L., Paul, A.J., Butler, J.M., Hutchens, D.E., Vaughan, J.L., Tranquilli, B.S.W., Cleale, R.M., Rulli, R.D., 2001. Safety of moxidectin canine SR (sustained release) injectable in ivermectin-sensitive Collies and in naturally infected mongrel dogs. In: Abstracts of the 10th Triennal Heartworm Symposium, 20-22 April 2001. San Antonio, TX, p. 42.
2. Fortin J.F., Slocombe J.O.D. Temperature requirement for the development of Dirofilaria immitis in Aedes trivittatus and Aedes vexans. Mosq. News. 41:1981;625-633.
3. Genchi, C., Solari Basano, F., Marrone, R.V., Petruschke, G., 1998. Canine and feline heartworm in Europe with special emphasis in Italy. In: Seward, R.L. (Ed.), Recent Advances in Heartworm Disease: Symposium 1998. American Heartworm Society, Batavia, IL, pp. 75-82.
4. Genchi C., Poglayen G., Kramer L.H., Venco L., Agostini A. Efficacy of moxidectin for the prevention of adult heartworm (Dirofilaria immitis) infection in dogs. Parasitologia. 42:2001;139-141.
5. King, R.R., Courtney, C.H., Aguilar, R., 1992. Heartworm prophylaxis with moxidectin: Field trial results from a hyperenzootic area. In: Soll, M.D. (Ed.), Proceedings of the Heartworm Symposium 1992. American Heartworm Society, Batavia, IL, pp. 179-181.
6. Lok, J.B., Knight, D.H. 1998. Laboratory verification of a seasonal heartworm transmission model. In: Seward, R.L. (Ed.), Recent Advances in Heartworm Disease: Symposium 1998. American Heartworm Society, Batavia, IL, pp. 15-20.
7. Lok J.B., Knight D.H., Wang G.T., Doscher M.E., Nolan T.J., Hendrick M.J., Steber W., Heaney K. Activity of an injectable, sustained-release formulation of moxidectin administered prophylactically to mixed-breed dogs to prevent infection with Dirofilaria immitis. Am. J. Vet. Res. 62:2001;1721-1726.
8. Magi M., Marconcini A., Sassetti M. Distribution of canine filariosis in Tuscany. Selezione Veterinaria (Italian). 30:1989;1185-1187.
9. McCall, J.W., McTier, T.L., Holmes, R.A., Greene, T., Strickland, J., Aguilar, R., 1992. Prevention of naturally acquired heartworm infection in heartworm-naïve beagles by oral administration of moxidectin at an interval of either 1 or 2 months. In: Soll, M.D. (Ed.), Proceedings of the Heartworm Symposium 1992. American Heartworm Society, Batavia, IL, pp. 169-177.
10. McTier, T.L., McCall, J.W., Dzimianski, M.T., Aguilar, R., Wood, I., 1992. Prevention of experimental heartworm infection in dogs with single, oral dose of moxidectin. In: Soll, M.D. (Ed.), Proceedings of the Heartworm Symposium 1992. American Heartworm Society, Batavia, IL, pp. 165-168.
11. Rossi L., Meneguz P.G., Gribaudo L., Balbo T. An epidemiological study of canine filariosis in north west Italy: what has changed in 25 years? Vet. Res. Commun. 20:1996;308-315.
12. Slocombe, J.O.D., Sugeoner, G.A., Srivastava, B., 1989. Determination of heartworm transmission period and its use in diagnosis and control. In: Otto, G.F. (Ed.), Proceedings of the Heartworm Symposium 1989. American Heartworm Society, Washington, DC, pp. 19-26.