Highly E-selective and effective synthesis of antiarthritic drug candidate S-2474 using quinone methide derivatives

Journal of Organic Chemistry

Volumn 67, Issue 1, 2002, Pages 125-128

  Inagaki, Masanao ^a   Haga, Nobuhiro ^a   Kobayashi, Makoto ^a   Ohta, Naoki ^a   Kamata, Susumu ^a   Tsuri, Tatsuo ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MECHANISTIC ASPECTS;

AROMATIC COMPOUNDS; ISOMERS; SYNTHESIS (CHEMICAL);

DERIVATIVES;

5 (3,5 DI TERT BUTYL 4 HYDROXYBENZYLIDENE) 2 ETHYL 1,2 ISOTHIAZOLIDINE 1,1 DIOXIDE; ANTIRHEUMATIC AGENT; QUINONE DERIVATIVE; S 2474; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STEREOCHEMISTRY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIRHEUMATIC AGENTS; CRYSTALLIZATION; CYCLIC S-OXIDES; INDOLEQUINONES; INDOLES; QUINONES; SOLVENTS; STEREOISOMERISM; THIAZOLES;

EID: 0037059529     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0106795     Document Type: Article

References (29)