Exercise anaerobic threshold and ventilatory efficiency identify heart failure patients for high risk of early death

Circulation

Volumn 106, Issue 24, 2002, Pages 3079-3084

  Gitt, Anselm K ^a   Wasserman, Karlman ^b   Kilkowski, Caroline ^a   Kleemann, Thomas ^a   Kilkowski, Andreas ^a   Bangert, Matthias ^a   Schneider, Steffen ^a   Schwarz, Armin ^a   Senges, Jochen ^a  

^a KLINIKUM LUDWIGSHAFEN   (Germany)

^b HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

Exercise; Heart failure; Prognosis; Transplantation; Ventilation

Indexed keywords

ADULT; AGED; ANAEROBIC THRESHOLD; ARTICLE; EVALUATION; EXERCISE TEST; FEMALE; FOLLOW UP; GAS EXCHANGE; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART TRANSPLANTATION; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; MORTALITY; MULTIVARIATE ANALYSIS; OXYGEN CONSUMPTION; PARAMETER; PATIENT CODING; PATIENT SELECTION; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; RISK ASSESSMENT;

AGE FACTORS; AGED; ANAEROBIC THRESHOLD; EXERCISE TEST; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE, CONGESTIVE; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; PULMONARY GAS EXCHANGE; RESPIRATORY FUNCTION TESTS; RISK ASSESSMENT; STROKE VOLUME; SURVIVAL ANALYSIS;

EID: 0037058867     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000041428.99427.06     Document Type: Article

References (25)

1. Cohn JN, Fowler MB, Bristow MR, et al. Safety and efficacy of carvedilol in severe heart failure. The U S Carvedilol Heart Failure Study Group. J Card Fail. 1997:3:173-179.
2. Packer M, Colucci WS, Sackner-Bernstein JD, et al. Double-blind, placebo-controlled study of the effects of carvedilol in patients with moderate to severe heart failure: The PRECISE Trial: Prospective Randomized Evaluation of Carvedilol on Symptoms and Exercise. Circulation. 1996;94:2793-2799.
3. Packer M, Bristow MR, Cohn JN, et al. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure: US Carvedilol Heart Failure Study Group. N Engl J Med. 1996;334:1349-1355.
4. Pamboukian SV, Aminbakhsh A, Thompson CR, et al. Carvedilol improves functional class in patients with severe left ventricular dysfunction referred for heart transplantation. Clin Transplant. 1999;13:426-431.
5. Cohn JN, Johnson GR, Shabetai R, et al. Ejection fraction, peak exercise oxygen consumption, cardiothoracic ratio, ventricular arrhythmias, and plasma norepinephrine as determinants of prognosis in heart failure: The V-He FT VA Cooperative Studies Group Circulation. 1993;87(suppl VI):VI-5-VI-16.
6. Francis GS, Goldsmith SR, Cohn JN. Relationship of exercise capacity to resting left ventricular performance and basal plasma norepinephrine levels in patients with congestive heart failure. Am Heart J. 1982; 104:725-731.
7. Francis GS, Goldsmith SR, Ziesche SM, et al. Response of plasma norepinephrine and epinephrine to dynamic exercise in patients with congestive heart failure. Am J Cardiol. 1982;49:1152-1156.
8. Smith RF, Johnson G, Ziesche S, et al. Functional capacity in heart failure: Comparison of methods for assessment and their relation to other indexes of heart failure: The V-He FT VA Cooperative Studies Group. Circulation. 1993;87(suppl VI):VI-88-VI-93.
9. Mancini DM, Eisen H, Kussmaul W, et al. Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Circulation. 1991;83:778-786.
10. Stevenson LW. Advanced congestive heart failure: Inpatient treatment and selection for cardiac transplantation. Postgrad Med. 1993;94:97-7. 112.
11. Stevenson LW. Role of exercise testing in the evaluation of candidates for cardiac transplantation. In: Wasserman K, ed. Exercise Gas Exchange in Heart Disease. Armonk, New York: Futura Publishing Company, Inc; 1996:271-286.
12. Stevenson LW, Steimle AE, Fonarow G, et al. Improvement in exercise capacity of candidates awaiting heart transplantation. J Am Coll Cardiol. 1995;25:163-170.
13. Stelken AM, Younis LT, Jennison SH, et al. Prognostic value of cardiopulmonary exercise testing using percent achieved of predicted peak oxygen uptake for patients with ischemic and dilated cardiomyopathy. J Am Coll Cardiol. 1996;27:345-352.
14. Osman AF, Mehra MR, Lavie CJ, et al. The incremental prognostic importance of body fat adjusted peak oxygen consumption in chronic heart failure. J Am Coil Cardiol. 2000;36:2126-2131.
15. Myers J, Gullestad L, Vagelos R, et al. Clinical, hemodynamic, and cardiopulmonary exercise test determinants of survival in patients referred for evaluation of heart failure. Ann Intern Med. 1998;129:286-293.
16. Mudge GH, Goldstein S, Addonizio LJ, et al. Twenty-fourth Bethesda conference: Cardiac transplantation. Task-Force 3: Recipient guidelines/prioritization. J Am Coll Cardiol. 1993;22:21-31.
17. Wasserman K, Hansen JE, Sue DY, et al. Principles of Exercise Testing and Interpretation. 2nd ed. Malvern, Pa: Lea & Febiger: 1994.
18. Chua TP, Ponikowski P, Harrington D, et al. Clinical correlates and prognostic significance of the ventilatory response to exercise in chronic heart failure. J Am Coll Cardiol. 1997;29:1585-1590.
19. Kleber FX, Vietzke G, Wernecke KD, et al. Impairment of ventilatory efficiency in heart failure: Prognostic impact. Circulation. 2000;101: 2803-2809.
20. Buchfuhrer MJ, Hansen JE, Robinson TE, et al. Optimizing the exercise protocol for cardiopulmonary assessment. J Appl Physiol. 1983;55: 1558-1564.
21. Beaver WL, Wasserman K, Whipp BJ. A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol. 1986;60: 2020-2027.
22. Older P, Hall A. The role of cardiopulmonary exercise testing for the preoperative evaluation of the elderly. In: Wasserman K, ed. Exercise Gas Exchange in Heart Disease. Armonk, New York: Futura Publishing Company, Inc; 1996:287-298.
23. Weber KT, Wilson JR, Janicki JS, et al. Exercise testing in the evaluation of the patient with chronic cardiac failure. Am Rev Respir Dis. 1984;129: S60-S62.
24. Weber KT, Janicki JS, Ward DM, et al. Measurement and interpretation of maximal oxygen uptake in patients with chronic cardiac or circulatory failure. J Clin Monit. 1987;3:31-37.
25. Stevenson LW. Selection and management of candidates for heart transplantation. Curr Opin Cardiol. 1996;11:166-173.