Comparison of 3D structures and AT1 binding properties of pyrazolidine-3,5-diones and tetrahydropyridazine-3,6-diones with parent antihypertensive drug irbesartan

Journal of Medicinal Chemistry

Volumn 45, Issue 21, 2002, Pages 4794-4798

  Le Bourdonnec, Bertrand ^a   Cauvin, Christine ^b   Meulon, Emmanuelle ^a   Yous, Saïd ^a   Goossens, Jean François ^c   Durant, François ^b   Houssin, Raymond ^a   Hénichart, Jean Pierre ^a  

^a Faculté des Sciences Pharmaceutiques et Biologiques Université de Lille   (France)

^b UNIVERSITY OF NAMUR   (Belgium)

^c UNIV LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 PYRAZOLIDINEDIONE; ALDOSTERONE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; IRBESARTAN; PHENYLBUTAZONE; RENIN; TETRAHYDROPYRIDAZINE 3,6 DIONE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BLOOD PRESSURE REGULATION; HYDROGEN BOND; ISOMERISM; MOLECULAR MODEL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0037057575     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010457z     Document Type: Article

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