FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines

Gene

Volumn 294, Issue 1-2, 2002, Pages 131-140

  Freyaldenhoven, Bettina S ^a   Fried, Cora ^a   Wielckens, Klaus ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

FOX transcription factor; Gene structure; Leukemia

Indexed keywords

ALANINE; CD34 ANTIGEN; COMPLEMENTARY DNA; MESSENGER RNA; PROLINE; PROTEIN FOXD4A; PROTEIN FOXD4B; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADULT; AMINO TERMINAL SEQUENCE; ARTICLE; BLOOD CELL; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA BINDING; DNA ISOLATION; EXON; FETUS; GENE FUNCTION; GENE ISOLATION; GENE LIBRARY; GENE STRUCTURE; GENETIC CODE; GENOME; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANTIGENS, CD34; BLOTTING, NORTHERN; CELL LINE; DNA, COMPLEMENTARY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEMATOPOIETIC STEM CELLS; HL-60 CELLS; HUMANS; JURKAT CELLS; LEUKEMIA; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; PROTEIN ISOFORMS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; U937 CELLS;

CANIDAE;

EID: 0037055275     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(02)00702-3     Document Type: Article

References (35)

1. Ang S.L., Rossant J. HNF3 is essential for node and notochord formation in mouse development. Cell. 78:1994;561-574.
2. Brandt J., Srour E., Van Besien K., Briddell R., Hoffman R. Cytokine-dependent long term marrow culture of highly enriched precursors of hematopoietic progenitor cells from human bone marrow. J. Clin. Invest. 86:1990;932-941.
3. Chen X., Rubock M.J., Whitman M. A transcriptional partner for MAD proteins in TGF-β signalling. Nature. 383:1996;691-696.
4. Clark K.L., Halay E.D., Lai E., Burley S.K. Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature. 364:1993;412-420.
5. Costa R.H. Tronche F., Yaniv M., Liver-Specific Gene Transcription. 1994;183-205 CRC Press, Boca Raton, FL.
6. Freyaldenhoven B.S., Freyaldenhoven M.P., Iacovoni J.S., Vogt P.K. Aberrant cell growth induced by avian winged helix proteins. Cancer Res. 57:1997;123-129.
7. Freyaldenhoven B.S., Freyaldenhoven M.P., Iacovoni J.S., Vogt P.K. Avian winged helix proteins CWH-1, CWH-2, and CWH-3 act as transcriptional repressors. Oncogene. 15:1997;483-488.
8. Galili N., Davis R.J., Fredericks W.J., Mukhopadhyay S., Rauscher F.J. III, Emanuel B.S., Rovera G., Barr F.G. Fusion of a fork head domain gene to PAX3 in solid tumour alveolar rhabdomyosarcoma. Nat. Genet. 5:1993;230-235.
9. Gu Y., Nakamura T., Alder H., Prasad R., Canaani O., Cimino G., Croce C.M., Canaani E. The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene. Cell. 71:1992;701-708.
10. Hatini V., Huh S.O., Herzlinger D., Soares V.C., Lai E. Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of winged helix transcription factor BF-2. Genes Dev. 10:1996;1467-1478.
11. Hillan J., Le Coniat M., Jonveaux P., Berger R., Bernard O.A. AF6q21, a novel partner of the MLL gene in t(6;11)(q21;q23), defines a forkhead transcriptional factor subfamily. Blood. 90:1997;3714-3719.
12. Hromas R., Moore J., Johnston T., Socha C., Klemsz M. Drosophila forkhead homologues are expressed in lineage-restricted manner in human hematopoietic cells. Blood. 81:1993;2854-2859.
13. - primitive human hematopoietic progenitors. Leukemia Lymphoma. 15:1994;439-444.
14. Kuzin B., Tillib S., Sedkov Y., Mizrokhi L., Mazo A. The Drosophila trithorax gene encodes a chromosomal protein and directory regulates the region-specific homeotic gene fork head. Genes Dev. 8:1994;2478-2490.
15. Lai E., Prezioso V.R., Smith E., Litvin O., Costa R.H., Darnell E. Jr. HNF-3α, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev. 4:1990;1427-1436.
16. Lai E., Prezioso V.R., Tao W., Chen W.S., J E. Jr, Darnell J.E. Jr. Hepatocyte nuclear factor 3α belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head. Genes Dev. 5:1991;416-427.
17. Lai E., Clark K.L., Burley S.K., Darnell J.E. Jr. Hepatocyte nuclear factor 3/fork head or 'winged helix' proteins: A family of diverse biologic function. Proc. Natl. Acad. Sci. USA. 90:1993;10421-10423.
18. Lehmann O.J., Ebenezer N.D., Jordan T., Fox M., Ocaka L., Payne A., Leroy B.P., Clark B.J., Hitchings R.A., Povey S., Khaw P.T., Bhattacharya S.S. Chromosomal duplication involving forkhead transcription factor gene FOXC1 causes iris hypoplasia and glaucoma. Am. J. Hum. Genet. 67:2000;1129-1135.
19. Li J., Vogt P.K. The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head. Proc. Natl. Acad. Sci. USA. 90:1993;4490-4494.
20. Lill M.C., Fuller J.F., Herzig R., Crooks G.M., Gasson J.C. The role of the homeobox gene HOXB7 in human myelomonocytic differentiation. Blood. 85:1995;692-697.
21. Lin K., Dorman J.B., Rodan A., Kenyon C. daf16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science. 278:1997;1319-1322.
22. Liu M.Y., Wu M.C. Induction of human monocyte cell line U937 and CSF-1 production by phorbol ester. Exp. Hematol. 20:1992;974-979.
23. Metcalf D. The molecular control of cell division, differentiation, commitment, and maturation in hematopoietic cells. Nature. 339:1989;27-30.
24. Nehls M., Pfeifer D., Schorpp M., Hedrich H., Boehm T. New member of the winged-helix protein family disrupted in mouse and rat nude mutations. Nature. 372:1994;103-106.
25. Nichols J., Nimer S.D. Transcription factors, translocations, and leukemia. Blood. 80:1992;2953-2963.
26. Orkin S.H. Transcription factors and hematopoietic development. J. Biol. Chem. 270:1995;4955-4958.
27. Overdier D.G., Porcella A., Costa R.H. The DNA-binding specificity of the hepatocyte nuclear factor 3/forkhead domain is influenced by amino acid residues adjacent to the recognition helix. Mol. Cell. Biol. 14:1994;2755-2766.
28. Parry P., Wei Y., Evans G. Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family. Genes Chromosomes Cancer. 11:1994;79-84.
29. Shapiro D.N., Sublett J.E., Li B., Downing J.R., Naeve C.W. Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma. Cancer Res. 53:1993;5108-5112.
30. Sutton J., Costa R., Klug M., Field L., Xu D., Largaespada D.A., Fletcher C.F., Jenkins N.A., Copeland N.G., Klemsz M., Hromas R. Genesis, a winged helix transcriptional repressor with expression restricted to embryonic stem cells. J. Biol. Chem. 271:1996;23126-23133.
31. Vogt P.K., Li J., Freyaldenhoven B.S. Relevations of a captive: retroviral Qin and the oncogenicity of winged helix proteins. Virology. 238:1997;1-7.
32. Weigel D., Jürgens G., Küttner F., Seifert E., Jäckle H. The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo. Cell. 57:1989;645-658.
33. Weinstein D.C., Ruiz i Altaba A., Chen W.S., Hoodless P., Prezioso V.R., Jessell T.M., Darnell J.E. Jr. The winged-helix transcription factor HNF-3β is required for notochord development in the mouse embryo. Cell. 78:1994;575-588.
34. Xu D., Yoder M., Sutton J., Hromas R. Forced expression of Genesis, a winged helix transcriptional repressor isolated from embryonic stem cells, blocks granulocytic differentiation of 32D myeloid cells. Leukemia. 12:1998;207-212.
35. Xuan S., Baptista C.A.:., Balas G., Tao W., Soares V.C., Lai E. Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron. 14:1995;1141-1152.