Asymmetric synthesis of (S)-ibuprofen by esterification with amides of (S)-lactic acid as chiral auxiliaries: Experimental and theoretical results

Tetrahedron Letters

Volumn 43, Issue 24, 2002, Pages 4325-4328

  Ammazzalorso, Alessandra ^a   Amoroso, Rosa ^a   Bettoni, Giancarlo ^a   De Filippis, Barbara ^a   Giampietro, Letizia ^a   Pierini, Marco ^b   Tricca, Maria Luisa ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

(S) ibuprofen; Dynamic kinetic resolution; Lactamides; Molecular mechanic calculations

Indexed keywords

4 DIMETHYLAMINOPYRIDINE; AMIDE; DICYCLOHEXYLCARBODIIMIDE; IBUPROFEN; LACTIC ACID;

ARTICLE; ASYMMETRIC SYNTHESIS; DIASTEREOISOMER; DRUG SYNTHESIS; ESTERIFICATION; KINETICS; MOLECULAR MECHANICS; POLYMERIZATION; STEREOCHEMISTRY;

EID: 0037053855     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)00792-X     Document Type: Article

References (21)