Synthesis and pharmacological properties of benzisothiazole/benzimidazole derivatives with acidic groups

Farmaco

Volumn 57, Issue 5, 2002, Pages 363-367

  Vicini, Paola ^a   Incerti, Matteo ^a   Amoretti, Loredana ^a   Ballabeni, Vigilio ^a   Tognolini, Massimiliano ^a   Barocelli, Elisabetta ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

Analgesic activity; Benzisothiazole benzimidazole; In vivo and in vitro pharmacological activities

Indexed keywords

(1H BENZIMIDAZOL 2 YL)ACETIC ACID; 5 [(1H BENZIMIDAZOL 2 YL)METHYL]TETRAZOLE; 5 [BENZ[D]ISOTHIAZOL 3 YL(PHENYL)METHYL]TETRAZOLE; ANTICOAGULANT AGENT; ANTIINFLAMMATORY AGENT; ANTIPYRETIC ANALGESIC AGENT; BENZIMIDAZOLE DERIVATIVE; BENZISOTHIAZOLE DERIVATIVE; ISOTHIAZOLE DERIVATIVE; PARACETAMOL; SPASMOLYTIC AGENT; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICOAGULATION; ANTIINFLAMMATORY ACTIVITY; ANTIPYRETIC ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; DRUG TOXICITY; FEMALE; HOT PLATE TEST; IN VIVO STUDY; MALE; NONHUMAN; RAT; STEREOSPECIFICITY; WRITHING TEST;

ACETAMINOPHEN; ACETIC ACID; ANALGESICS; ANIMALS; BENZIMIDAZOLES; ESCHERICHIA COLI; FEMALE; GUINEA PIGS; ILEUM; LETHAL DOSE 50; LIPOPOLYSACCHARIDES; MALE; MICE; PAIN; PAIN MEASUREMENT; PARASYMPATHOLYTICS; PLATELET AGGREGATION INHIBITORS; RATS; RATS, WISTAR; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 0037052047     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(02)01219-3     Document Type: Article

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