Phenytoin toxicity as a result of 5-fluorouracil administration

New Zealand Medical Journal

Volumn 115, Issue 1159, 2002, Pages

  Rosemergy, Ian ^a   Findlay, Michael ^b  

^a HUTT HOSPITAL   (New Zealand)

^b WELLINGTON HOSPITAL   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

CONJUGATED ESTROGEN; FLUOROURACIL; LOW MOLECULAR WEIGHT HEPARIN; PHENYTOIN; ANTICONVULSIVE AGENT; ANTINEOPLASTIC ANTIMETABOLITE;

ABDOMINAL PAIN; ADULT; ARTICLE; ATAXIA; BALANCE DISORDER; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CASE REPORT; DRUG BLOOD LEVEL; DRUG CLEARANCE; EPILEPSY; FEMALE; HEADACHE; HUMAN; MUSCLE TONE; MUSCLE WEAKNESS; RECTUM CARCINOMA; RECTUM HEMORRHAGE; RECTUM RESECTION; SEIZURE; SENSORY DYSFUNCTION; SUBCLAVIAN VEIN; VEIN THROMBOSIS; VERTIGO; VISUAL IMPAIRMENT; VOMITING; DRUG INTERACTION; METABOLISM; MIDDLE AGED; RECTUM TUMOR;

ANTICONVULSANTS; ANTIMETABOLITES, ANTINEOPLASTIC; DRUG INTERACTIONS; EPILEPSY; FEMALE; FLUOROURACIL; HUMANS; MIDDLE AGED; PHENYTOIN; RECTAL NEOPLASMS;

EID: 0037047773     PISSN: 11758716     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. O'Connell MJ, Martenson JA, Wieand HS et al. Improving adjuvant therapy for rectal cancer by combining protracted infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 1994; 331: 502-7.
2. Porter RJ, Meldrum BS. Antiepileptic drugs. In: Katzung BG, editor. Basic and clinical pharmacology. 6th ed. Connecticut: Appleton and Lange: 1995. p361-80.
3. Lennard L. Therapeutic drug monitoring of antimetabolic cytotoxic drugs. Br J Clin Pharmacol 1999; 2: 131-43.
4. Gilbar P, Brodribb TR. Phenytoin and fluorouracil interaction. Am Pharmacother 2001; 35: 1367-70.
5. Naranjo CA, Busto U, Sellers EM et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981; 30: 239-45.