Synthesis and antifungal activity of the 2,2,5-tetrahydrofuran regioisomers of SCH 51048

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 13, 2002, Pages 1739-1742

  Lovey, Raymond G ^a   Saksena, Anil K ^a   Girijavallabhan, Viyyoor M ^a   Blundell, Paul ^a   Guzik, Henry ^a   Loebenberg, David ^a   Parmegiani, Raulo M ^a   Cacciapuoti, Anthony ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SCH 51048; TETRAHYDROFURAN DERIVATIVE; ANTIFUNGAL AGENT; BENZENE; FURAN DERIVATIVE; OXYGEN; TETRAHYDROFURAN; TRIAZOLE DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; BINDING SITE; CONTROLLED STUDY; DERMATOPHYTE; DRUG STRUCTURE; DRUG SYNTHESIS; EPOXIDATION; FUNGUS; ISOMERISM; NONHUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; CHEMISTRY; IN VITRO STUDY; MICROBIOLOGICAL EXAMINATION; STEREOISOMERISM; SYNTHESIS;

ANTIFUNGAL AGENTS; BENZENE; BINDING SITES; FURANS; IN VITRO; MICROBIAL SENSITIVITY TESTS; OXYGEN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 0037042767     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00282-2     Document Type: Article

References (13)