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Volumn 12, Issue 13, 2002, Pages 1697-1700

Antifungal sordarins. Part 4: Synthesis and structure-activity relationships of 3′,4′-fused alkyl-tetrahydrofuran derivatives

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; GM 193663; GR 135402; GR 163598; SORDARIN DERIVATIVE; SUGAR; TETRAHYDROFURAN DERIVATIVE; UNCLASSIFIED DRUG; FLUCONAZOLE; FURAN DERIVATIVE; INDENE DERIVATIVE; SORDARIN; TETRAHYDROFURAN;

EID: 0037042759     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00293-7     Document Type: Article
Times cited : (14)

References (10)
  • 9
    • 0009484257 scopus 로고    scopus 로고
    • 1H NMR spectra. In particular, it is noteworthy the effect exerted by the position of the alkyl substituent on the coupling constants for protons at position 1′ of the sugar moieties in S isomers (alkyl substituents in endo position). Molecular modelling studies have suggested that this effect could be attributed to a conformational change in the six-membered ring, which takes a 'twisted boat'-like conformation in order to accomodate the substituent at endo position. These studies will be the subject matter of a future paper.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.