No evidence of an association between a functional monoamine oxidase A gene polymorphism and completed suicides

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 114, Issue 3, 2002, Pages 340-342

  Ono, Hisae ^a   Shirakawa, Osamu ^a   Nishiguchi, Naoki ^a   Nishimura, Akiyoshi ^b   Nushida, Hideyuki ^a   Ueno, Yasuhiro ^a   Maeda, Kiyoshi ^a  

^a KOBE UNIVERSITY   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Association study; MAOA uVNTR polymorphism; Suicide

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A;

ADULT; AGGRESSION; ALLELE; ARTICLE; BRAIN METABOLISM; CONTROL SYSTEM; FEMALE; GENE FREQUENCY; GENE LOCATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; HUMAN; IMPULSIVENESS; MAJOR CLINICAL STUDY; MALE; NEUROTRANSMITTER RELEASE; PRIORITY JOURNAL; SUICIDE; TANDEM REPEAT;

ADULT; AGED; ALLELES; DNA; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MINISATELLITE REPEATS; MONOAMINE OXIDASE; POLYMORPHISM, GENETIC; SUICIDE;

EID: 0037041327     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.10237     Document Type: Article

References (25)

1. Neurotransmitters and suicidal behavior: The evidence from cerebrospinal fluid studies
2. Dinucleotide repeat polymorphism at the MAOA locus
3. Aggression, suicide, and serotonin: Relationships to CSF amine metabolites
4. Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A
5. X-linked borderline mental retardation with prominent behavioral disturbance: Phenotype, genetic localization, and evidence for disturbed monoamine metabolism
6. The biochemical high-risk paradigm: Behavioral and familial correlates of low platelet monoamine oxidase activity
7. Suicide attempts, platelet monoamine oxidase and the average evoked response
8. Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA
9. Organization of the human monoamine oxidase genes and long-range physical mapping around them
10. Human brain serotonin synthesis capacity measured in vivo with alpha-[C-11] methyl-L-tryptophan
11. Human platelet monoamine oxidase: A useful enzyme in the study of psychiatric disorders?
12. Lowered monoamine oxidase activity in brains from alcoholic suicides
13. Suicide and schizophrenia: A nationwide psychological autopsy study on age-and sex-specific clinical characteristics of 92 completed suicides with schizophrenia
14. Characterization of a highly polymorphic region near the first exon of the human MAOA gene containing a GT dinucleotide and a novel VNTR motif
15. A promoter polymorphism in the monoamine oxidase A gene and its relationships to monoamine metabolite concentrations in CSF of healthy volunteers
16. A functional polymorphism in the promoter region of monoamine oxidase-A gene and mood disorders
17. Postmortem monoamine oxidase enzyme kinetics in the frontal cortex of completed suicides and controls
18. The neurobiology of suicide risk: A review for the clinician
19. A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivity
20. Platelet markers of suicidality
21. Human monoamine oxidase gene (MAOA): Chromosome position (Xp21-p11) and DNA polymorphism
22. A functional polymorphism in the monoamine oxidase A gene promoter
23. Brain gamma-aminobutyrate transaminase and monoamine oxidase activities in completed suicides
24. The world health report 2001
25. Tryptophan, 5-hydroxyindoleacetic acid and indoleacetic acid in human cerebrospinal fluid: Interrelationships and the influence of age, sex, epilepsy and anticonvulsant drugs