Effect of intravenous bisphosphonates on release of basic fibroblast growth factor in serum of patients with cancer-associated hypercalcemia

Life Sciences

Volumn 70, Issue 16, 2002, Pages 1947-1960

  Zimering, Mark B ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Basic fibroblast growth factor; Bisphosphonate; Hypercalcemia; Malignancy

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BISPHOSPHONIC ACID DERIVATIVE; PARATHYROID HORMONE RELATED PROTEIN;

ADULT; AGED; BLOOD LEVEL; BONE METASTASIS; CANCER; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; HYPERCALCEMIA; MALE; OSTEOLYSIS; PROTEIN SECRETION; RANDOMIZED CONTROLLED TRIAL; SERUM;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CATTLE; CELLS, CULTURED; DIPHOSPHONATES; FEMALE; FIBROBLAST GROWTH FACTOR 2; HUMANS; HYPERCALCEMIA; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; NEOPLASMS;

EID: 0037040599     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01548-X     Document Type: Conference Paper

References (37)

1. Structural characterization and biological functions of fibroblast growth factor
2. Identical mutations in three different fibroblast growth factor receptor genes in autosomal dominant craniosynostosis syndrome
3. Isolation of brain fibroblast growth factor by heparin - Sepharose affinity chromatography: Identity with pituitary fibroblast growth factor
4. Fibroblast growth factor in the human placenta
5. Isolation of fibroblast growth factor from bovine adrenal gland: Physiochemical and biological characterization
6. Corpus luteum angiogenic factor is related to fibroblast growth factor
7. Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin - Sepharose
8. Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF
9. 125I)(Tyr10) FGF(1-10) by serum in vitro and involvement in the determination of circulating FGF by RIA
10. Injury-induced release of basic fibroblast growth factor from bovine aortic endothelium
11. Increased basic fibroblast growth factor in plasma from multiple endocrine neoplasia type 1: Relation to pituitary tumor
12. Treatment of cancer-associated hypercalcemia with alendronate sodium: A randomized double-blind comparison with etidronate
13. Increased basic fibroblast growth factor-like substance in plasma from a subset of middle-aged or elderly male diabetic patients with microalbuminuria or proteinuria
14. Increased level of basic fibroblast growth factor (bFGF) in sera of patients with malignant tumors
15. Mitogenic activity toward human breast cancer cell line MCF-7 of two bFGFs purified from sera of breast cancer patients: Co-operative role of cathepsin D
16. Modulation of type beta transforming growth factor activity in bone cultures by osteotropic hormones
17. Effect of oral alendronate on bone mineral density and the incidence of fractures in post-menopausal osteoporosis. The Alendronate Phase III Osteoporosis Treatment Study Group
18. Comparative study of alendronate versus etidronate for the treatment of Paget's disease of bone
19. Circulating PTHrP concentration in tumor-induced hypercalcemia: Influence on the response to bisphosphonate and changes after therapy
20. Effects of a single intracoronary injection of basic fibroblast growth factor in stable angina pectoris
21. In vivo involvement of heparan sulfate proteoglycan in the bioavailability, internalization and catabolism of exogenous basic fibroblast growth factor
22. Acid extrusion is induced by osteoclast attachment to bone: Inhibition by alendronate and calcitonin
23. r 52,000 cathepsin D secreted by breast cancer cells
24. Increased secretion, altered processing and glycosylation of pro-cathepsin D in human mammary cancer cells
25. Phospholipase C release of basic fibroblast growth factor from human bone marrow cultures as a biologically active complex with a phosphatidylinositol-anchored heparan sulfate proteoglycan
26. Bisphosphonates induce apoptosis in human myeloma cell lines: A novel anti-tumor activity
27. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
28. Parathyroid hormone regulates the expression of fibroblast growth factor-2 mRNA and fibroblast growth factor receptor mRNA in osteoblastic cells
29. Stimulation of renin release in perfused kidney by low calcium and high magnesium
30. PTH secretion in vivo and in vitro: Regulation by calcium and other secretagogues
31. Expression of basic fibroblast growth factor and its receptor in the rat subfornical organ
32. Water deprivation upregulates ANGII AT1 binding and mRNA in rat subfornical organ and anterior pituitary
33. Conditions for stimulation of renin release by cyclic AMP in anaesthetized dogs
34. Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth
35. Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
36. Autosomal dominant hypophosphatemic rickets is assoicated with mutations in FGF23