N-methyl-D-aspartate-induced long-term depression is associated with a decrease in postsynaptic protein kinase C substrate phosphorylation in rat hippocampal slices

Neuroscience Letters

Volumn 320, Issue 3, 2002, Pages 129-132

  Van Dam, Els J M ^a   Ruiter, Bert ^a   Kamal, Amer ^a   Ramakers, Geert M J ^a   Gispen, Willem Hendrik ^a   De Graan, Pierre N E ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Growth associated protein 43 B 50; Hippocampus; Phosphorylation; Protein phosphatase; RC3 neurogranin; Synaptic plasticity

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROGRANIN; NEUROMODULIN; PROTEIN KINASE C;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; DISEASE COURSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; HIPPOCAMPUS; IMMUNOPRECIPITATION; INCUBATION TIME; MALE; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRESYNAPTIC NERVE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REDUCTION;

2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; CALMODULIN-BINDING PROTEINS; DOWN-REGULATION; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GAP-43 PROTEIN; HIPPOCAMPUS; MALE; N-METHYLASPARTATE; NERVE TISSUE PROTEINS; NEURAL INHIBITION; NEUROGRANIN; NEURONAL PLASTICITY; PHOSPHORYLATION; PROTEIN KINASE C; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 0037040527     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(02)00037-X     Document Type: Article

References (21)

1. Purification and characterization of a brain-specific protein kinase C substrate, neurogranin (p17)
2. Long-term depression in hippocampus
3. Determination of changes in the phosphorylation state of the neuron-specific protein kinase C substrate B-50 (GAP-43) by quantitative immunoprecipitation
4. Antibodies to postsynaptic PKC substrate neurogranin prevent long-term potentiation in hippocampal CA1 neurons
5. RC3/neurogranin, a postsynaptic calpacitin for setting the response threshold to calcium influxes
6. Pre- and postsynaptic localization of RC3/neurogranin in the adult rat spinal cord: An immunohistochemical study
7. Calcium-sensitive interaction between calmodulin and modified forms of rat brain neurogranin/RC3
8. Chemical LTD in the CA1 field of the hippocampus from young and mature rats
9. Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression
10. Increased phosphorylation of a 17-kDa protein kinase C substrate (P17) in long-term potentiation
11. NMDA induces long-term synaptic depression and dephosphorylation of the GluR1 subunit of AMPA receptors in hippocampus
12. Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity
13. B-50, the growth associated protein-43: Modulation of cell morphology and communication in the nervous system
14. Involvement of neurogranin in the modulation of calcium/calmodulin-dependent protein kinase II, synaptic plasticity, and spatial learning: A study with knock out mice
15. Interactions between neurogranin and calmodulin in vivo
16. Temporal differences in the phosphorylation state of pre- and postsynaptic protein kinase C substrates B-50/GAP-43 and neurogranin during long-term potentiation
17. LTD in the CA1 field is associated with a transient decrease in pre- and postsynaptic PKC substrate phosphorylation
18. Activation of pre- and postsynaptic protein kinase C during tetraethylammonium-induced long-term potentiation in the CA1 fields of the hippocampus
19. Neurogranin: Immunocytochemical localization of a brain-specific protein kinase C substrate
20. Dephosphorylation of protein kinase C substrates, neurogranin, neuromodulin, and MARCKS, by calcineurin and protein phosphatases 1 and 2A