Photostability profiles of the experimental antimetastatic ruthenium complex NAMI-A

Journal of Pharmaceutical and Biomedical Analysis

Volumn 30, Issue 4, 2002, Pages 1287-1296

  Bouma, Marjan ^a   Nuijen, Bastiaan ^a   Jansen, Martine T ^a   Sava, Gianni ^b,c   Bult, Auke ^d   Beijnen, Jos H ^a,d  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b Callerio Foundation   (Italy)

^c SIGEA Srl   (Italy)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

NAMI A; Photodegradation; Photostability

Indexed keywords

ANTIMETASTATIC AGENT; BENZYL ALCOHOL; CURCUMIN; DIMETHYL SULFOXIDE; IMIDAZOLIUMTETRACHLORO(DIMETHYLSULFOXIDE)IMIDAZOLE RUTHENIUM COMPLEX; PROPYLENE GLYCOL; RUTHENIUM COMPLEX; STABILIZING AGENT; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION (PARAMETERS); DARKNESS; DRUG DEGRADATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG STABILITY; DRUG STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID; PH; PHOTODEGRADATION; PRIORITY JOURNAL; SOLID; ULTRAVIOLET SPECTROPHOTOMETRY;

ANTINEOPLASTIC AGENTS; DIMETHYL SULFOXIDE; DRUG STABILITY; LIGHTING; NEOPLASM METASTASIS; ORGANOMETALLIC COMPOUNDS; RUTHENIUM;

EID: 0037038420     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(02)00458-2     Document Type: Article

References (24)

1. Sava G., Alessio E., Bergamo A., Mestroni G. Clarke M.J., Sadler P.J., Biological Inorganic Chemistry. 1:1999;Verlag, Berlin, Germany.
2. Mestroni G., Alessio E., Sava G., Pacor S., Coluccia M., Boccarelli A. Metal-Based Drugs. 1:1994;41-63.
3. Sava G., Capozzi I., Clerici K., Gagliardi G., Alessio E., Mestroni G. Clin. Exp. Metastasis. 16:1998;371-379.
4. Bergamo A., Gagliardi R., Scarcia V., Furlani A., Alessio E., Mestroni G., Sava G. J. Pharmacol. Exp. Ther. 289:1999;559-564.
5. Cocchietto M., Sava G. Pharmacol. Toxicol. 87:2000;193-197.
6. Sava G., Cocchietto M. In Vivo. 14:2000;741-744.
7. Sava G., Bergamo A., Cocchietto M., Flaibani A., Gava B., Pintus G., Sorc A., Tadolini B., Ventura C., Zorzet S. Clin. Cancer Res. 6:2000;4566s. abstract # 501.
8. Zorzet S., Bergamo A., Cocchietto M., Sorc A., Gava B., Alessio E., Iengo E., Sava G. J. Pharmacol. Exp. Ther. 295:2000;927-933.
9. Vacca A., Bruno M., Boccarelli A., Coluccia M., Ribatti D., Bergamo A., Garbisa S., Sartor L., Sava G. Br. J. Cancer. 86:2002;993-998.
10. ICH Harmonised Tripartite Guideline Topic Q1B, Stability Testing: Photostability Testing of New Drug Substances and Products. Available from: http://www.emea.eu.int/pdfs/human/ich/027995en.pdf.
11. M. Bouma, B. Nuijen, M.T. Jansen, G. Sava, F. Picotti, A. Flaibani, A. Bult J.H. Beijnen, J. Pharm. Biomed. Anal., in press
12. M. Bouma, B. Nuijen, M.T. Jansen, G. Sava, A. Flaibani, A. Bult, J.H. Beijnen, A Kinetic Study Into the Stability of NAMI-A, submitted for publication.
13. Yoshioka S., Ishihara Y., Terazono T., Tsunakawa N., Murai M., Yasuda T., Kitamura, Kunihiro Y., Sakai K., Hirose Y., Tonooka K., Takayama K., Imai F., Godo M., Matsuo M., Nakamura K., Aso Y., Kojima S., Takeda Y., Terao T. Drug Dev. Ind. Pharm. 20:1994;2049-2062.
14. Moore D.E. J. Pharm. Biomed. Anal. 5:1987;441-453.
15. Christensen K.L., Christensen J.Ø., Frokjaer S., Langballe P., Hansen L.L. Eur. J. Pharm. Sci. 9:2000;317-321.
16. Sava G., Bergamo A., Zorzet S., Sava B., Casarsa C., Cocchietto M., Furlani A., Scarcia V., Serli B., Iengo E., Alessio E., Mestroni G. Eur. J. Cancer. 38:2002;427-435.
17. Asker A.F., Islam M.S. PDA J. Pharm. Sci. Techn. 48:1994;205-210.
18. Wood M.J., Irvin W.J., Scott D.K. J. Clin. Pharm. Ther. 15:1990;291-300.
19. Chinnian D., Asker A.F. PDA J. Pharm. Sci. Techn. 50:1996;94-98.
20. Asker A.F., Jackson D. Drug Dev. Ind. Pharm. 12:1986;385-396.
21. Asker A.F., Harris C.W. Drug Dev. Ind. Pharm. 14:1988;733-746.
22. Thoma K., Klimek R. Int. J. Pharm. 67:1991;169-175.
23. Islam M.S., Asker A.F. J. Pharm. Sci. Techn. 48:1994;38-40.
24. Beijnen J.H., Flora K.P., Halbert G.W., Henrar R.E.C., Slack J.A. Br. J. Cancer. 72:1995;210-218.