Synthesis and evaluation of thymidine-5′-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 19, 2002, Pages 2695-2698

  Vanheusden, Veerle ^a   Munier Lehmann, Hélène ^b   Pochet, Sylvie ^b   Herdewijn, Piet ^a,c   Van Calenbergh, Serge ^a  

^a GHENT UNIVERSITY   (Belgium)

^b INSTITUT PASTEUR   (France)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMYCOBACTERIAL AGENT; AZIDE; ENZYME INHIBITOR; HALIDE; THYMIDINE PHOSPHATE; THYMIDYLATE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANTITUBERCULAR AGENTS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; KINETICS; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; NUCLEOSIDE-PHOSPHATE KINASE; THYMIDINE MONOPHOSPHATE;

MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 0037037402     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00551-6     Document Type: Article

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