Probing the 2,4-dichlorophenoxyacetate/α-ketoglutarate dioxygenase substrate-binding site by site-directed mutagenesis and mechanism-based inactivation

Biochemistry

Volumn 41, Issue 31, 2002, Pages 9787-9794

  Dunning Hotopp, Julie C ^a,b   Hausinger, Robert P ^a,c  

^a Michigan State University ^*  (United States)

^b J CRAIG VENTER INSTITUTE   (United States)

^c Michigan State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES;

CATALYSIS; ENZYMES; HERBICIDES; MUTAGENESIS; ORGANIC ACIDS;

BIOCHEMISTRY;

2 OXOGLUTARIC ACID; 2,4 DICHLOROPHENOXYACETIC ACID; OXYGENASE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SUBSTRATE; MASS SPECTROMETRY; OXIDATION; PRIORITY JOURNAL; PROTEIN PURIFICATION; SITE DIRECTED MUTAGENESIS;

ALKYLATION; AMINO ACID SEQUENCE; KINETICS; LIGANDS; MIXED FUNCTION OXYGENASES; MOLECULAR PROBES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; SUBSTRATE SPECIFICITY;

EID: 0037031286     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026057a     Document Type: Article

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